Owen SmithConsultant Paediatric Haematologist, Professor
Professor of Paediatric and Adolescent Medicine, UCD; Consultant Paediatric Haematologist, Our Lady’s Children’s Hospital, Crumlin; Chief Academic Lead to the Children’s Hospital Group; Hon. Regius Professor of Physic [1637], TCD
Professor Owen Smith CBE is a principal investigator at the National Children’s Research Centre, Crumlin and Systems Biology Ireland, University College Dublin. His two main areas of research have focused on evidence-based randomised peer-reviewed haemato-oncology clinical trials with a focus on clinical questions within all domains of paediatric and adolescent blood and cancer and the elucidation of the relationship between the protein C activation pathway and systemic inflammatory response sepsis syndromes.
One of Professor Smiths’ major contributions to Irish medicine has been through the promotion of clinical research as evidenced by; a significant expansion of clinical paediatric scholarship with excellent research outputs, a strengthening of national and international academic collaborations, and the nurturing, education, and career development of the present generation of Irish consultant paediatric haematologists. In addition, Professor Smith’s has a strong record of championing significant national developments in child and adolescent health in this country over the two decades.
In 2015 Professor Smith conferred honorary Commander in the Most Excellent Order of the British Empire (CBE) for his life-long work on cancer in children and adolescents by Queen Elizabeth, on the advice of the Foreign and Commonwealth Office.
Owen SmithConsultant Paediatric Haematologist, Professor
The list of publications below is automatically derived from MEDLINE/PubMed. As a result, there may be incorrect or missing publications.
| Regan IE, Cox D, Kelleher ST, Nolan B, Shaw K, Smith OP, McMahon CJ, 2023 Nov 22, Towards a greater understanding of reduced response to aspirin in children with congenital heart disease post-cardiac surgery using immature platelet fraction. Thromb Res, DOI: 10.1016/j.thromres.2023.11.014 |
| Trinquand A, Betts DR, Harte S, Sills A, Rooney S, Barrett N, Storey L, Malone A, O'Marcaigh A, Smith OP, 2023 Nov 1, Adapted risk stratification and intensive chemotherapy abrogate the poor prognosis of pediatric B acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21): a National cohort analysis. Leuk Lymphoma, DOI: 10.1080/10428194.2023.2276061 |
| Vinci L, Flotho C, Noellke P, Lebrecht D, Masetti R, de Haas V, De Moerloose B, Dworzak M, Hasle H, Güngör T, Starý J, Turkiewicz D, Ussowicz M, de Heredia CD, Buechner J, Jahnukainen K, Kallay K, Bodova I, Smith OP, Zecca M, Bresters D, Lang P, Masmas TN, Meisel R, Pichler H, Erlacher M, Göhring G, Locatelli F, Strahm B, Niemeyer CM, Yoshimi A, 2023 May, Second allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft. Bone Marrow Transplant, DOI: 10.1038/s41409-023-01942-4 |
| Smith OP, 2022 Oct, Denis Burkitt: A cancer, the virus and the prevention of man-made diseases. Br J Haematol, DOI: 10.1111/bjh.18411 |
| Toksvang LN, Als-Nielsen B, Bacon C, Bertasiute R, Duarte X, Escherich G, Helgadottir EA, Johannsdottir IR, Jónsson ÓG, Kozlowski P, Langenskjöld C, Lepik K, Niinimäki R, Overgaard UM, Punab M, Räty R, Segers H, van der Sluis I, Smith OP, Strullu M, Vaitkevičienė G, Wik HS, Heyman M, Schmiegelow K, 2022 May 2, Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol. BMC Cancer, DOI: 10.1186/s12885-022-09522-3 |
| O'Regan N, Gegenbauer K, Gleeson EM, Fukudome K, O'Sullivan JM, Drakeford C, Dalton N, Chion A, Brophy TM, Smith OP, Preston RJS, O'Donnell JS, 2022 Aug 1, Hemostatic and protein C pathway dysfunction in the pathogenesis of experimental cerebral malaria. Haematologica, DOI: 10.3324/haematol.2021.280450 |
| Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, Masetti R, Schmugge M, De Moerloose B, Catala A, Kállay K, Turkiewicz D, Hasle H, Buechner J, Jahnukainen K, Ussowicz M, Polychronopoulou S, Smith OP, Fabri O, Barzilai S, de Haas V, Baumann I, Schwarz-Furlan S, European Working Group of MDS in Children (EWOG-MDS), Niewisch MR, Sauer MG, Burkhardt B, Lang P, Bader P, Beier R, Müller I, Albert MH, Meisel R, Schulz A, Cario G, Panda PK, Wehrle J, Hirabayashi S, Derecka M, Durruthy-Durruthy R, Göhring G, Yoshimi-Noellke A, Ku M, Lebrecht D, Erlacher M, Flotho C, Strahm B, Niemeyer CM, Wlodarski MW, 2021 Dec, Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med, DOI: 10.1038/s41591-021-01632-y |
| Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, Masetti R, Schmugge M, De Moerloose B, Catala A, Kállay K, Turkiewicz D, Hasle H, Buechner J, Jahnukainen K, Ussowicz M, Polychronopoulou S, Smith OP, Fabri O, Barzilai S, de Haas V, Baumann I, Schwarz-Furlan S, European Working Group of MDS in Children (EWOG-MDS), Niewisch MR, Sauer MG, Burkhardt B, Lang P, Bader P, Beier R, Müller I, Albert MH, Meisel R, Schulz A, Cario G, Panda PK, Wehrle J, Hirabayashi S, Derecka M, Durruthy-Durruthy R, Göhring G, Yoshimi-Noellke A, Ku M, Lebrecht D, Erlacher M, Flotho C, Strahm B, Niemeyer CM, Wlodarski MW, 2021 Oct, Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med, DOI: 10.1038/s41591-021-01511-6 |
| McCarthy P, Cotter M, Smith OP, 2022 Feb, Autosomal dominant Shwachman-Diamond syndrome with a novel heterozygous missense variant in the SRP54 gene causing severe phenotypic features. Br J Haematol, DOI: 10.1111/bjh.17853 |
| Besani C, Dunne A, D'Arcy-Bewick S, Owens C, Pears J, O'Marcaigh A, Malone A, Fortune G, Capra M, Smith OP, 2021 Aug 19, The Development of a National Paediatric Psycho-Oncology Service. Ir Med J, DOI: 10.1111/bjh.17853 |
| McCarthy P, Harford J, O'Marcaigh A, Malone A, Evans P, Sills A, Storey L, Rooney S, Betts D, O'Sullivan MJ, McDermott M, Bond J, Trinquand A, Smith OP, 2021 Aug, Ongoing excellent outcomes with reduced toxicities following integration of molecular targeted therapies in pediatric anaplastic large cell lymphoma. Leuk Lymphoma, DOI: 10.1080/10428194.2021.1894644 |
| O'Rourke E, Malone A, O'Marcaigh A, Storey L, Betts D, McDermott M, Smith OP, 2020 Jan 16, Burkitt Lymphoma/Leukaemia in Children & Young Adolescents. Ir Med J, DOI: 10.1080/10428194.2021.1894644 |
| Dowling GP, Piccin A, Gavin KT, Betts DR, Malone A, Cotter M, Sills A, Evans P, O' Marcaigh A, Smith OP, 2020 Aug, A retrospective study of myeloid leukaemia in children with Down syndrome in Ireland. Ir J Med Sci, DOI: 10.1007/s11845-020-02181-y |
| Piccin A, Bacigalupo A, Zini G, Hamidieh AA, Bianchi M, Sica S, Valentini CG, Wolf D, Dazzi F, Fontanella F, Krampera M, Field S, Smith OP, 2019 Apr, Is platelet gel safe enough for neutropenic patients? Transfus Apher Sci, DOI: 10.1016/j.transci.2019.02.004 |
| Piccin A, Murphy C, Eakins E, Rondinelli MB, Daves M, Vecchiato C, Wolf D, Mc Mahon C, Smith OP, 2019 Apr, Insight into the complex pathophysiology of sickle cell anaemia and possible treatment. Eur J Haematol, DOI: 10.1111/ejh.13212 |
| Tummala H, Dokal AD, Walne A, Ellison A, Cardoso S, Amirthasigamanipillai S, Kirwan M, Browne I, Sidhu JK, Rajeeve V, Rio-Machin A, Seraihi AA, Duncombe AS, Jenner M, Smith OP, Enright H, Norton A, Aksu T, Özbek NY, Pontikos N, Cutillas P, Dokal I, Vulliamy T, 2018 Jul 24, Genome instability is a consequence of transcription deficiency in patients with bone marrow failure harboring biallelic ERCC6L2 variants. Proc Natl Acad Sci U S A, DOI: 10.1073/pnas.1803275115 |
| Malone A, Smith OP, 2017 Oct, Nelarabine toxicity in children and adolescents with relapsed/refractory T-ALL/T-LBL: can we avoid throwing the baby out with the bathwater? Br J Haematol, DOI: 10.1111/bjh.14875 |
| Gleeson EM, McDonnell CJ, Soule EE, Willis Fox O, Rushe H, Rehill A, Smith OP, O'Donnell JS, Preston RJS, 2017 Nov, A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective protease-activated receptor 1 signaling. J Thromb Haemost, DOI: 10.1111/jth.13807 |
| Malone A, Wlodarski M, Nolan B, Smyth L, Smith OP, 2017 Apr, Transient myeloproliferative disorder in an infant with PTPN11 mutation. Br J Haematol, DOI: 10.1111/bjh.14517 |
| O'Rafferty C, O'Brien M, Smyth E, Keane S, Robinson H, Lynam P, O'Marcaigh A, Smith OP, 2016 May, Administration of G-CSF from day +6 post-allogeneic hematopoietic stem cell transplantation in children and adolescents accelerates neutrophil engraftment but does not appear to have an impact on cost savings. Pediatr Transplant, DOI: 10.1111/petr.12670 |
| O'Regan N, Moxon C, Gegenbauer K, O'Sullivan JM, Chion A, Smith OP, Preston RJ, Brophy TM, Craig AG, O'Donnell JS, 2016 Apr, Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria. Thromb Haemost, DOI: 10.1160/TH15-10-0796 |
| Cseh AM, Niemeyer CM, Yoshimi A, Catala A, Frühwald MC, Hasle H, van den Heuvel-Eibrink MM, Lauten M, De Moerloose B, Smith OP, Bernig T, Gruhn B, Kulozik AE, Metzler M, Olcay L, Suttorp M, Furlan I, Strahm B, Flotho C, 2016 Mar, Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group. Br J Haematol, DOI: 10.1111/bjh.13915 |
| Wlodarski MW, Hirabayashi S, Pastor V, Starý J, Hasle H, Masetti R, Dworzak M, Schmugge M, van den Heuvel-Eibrink M, Ussowicz M, De Moerloose B, Catala A, Smith OP, Sedlacek P, Lankester AC, Zecca M, Bordon V, Matthes-Martin S, Abrahamsson J, Kühl JS, Sykora KW, Albert MH, Przychodzien B, Maciejewski JP, Schwarz S, Göhring G, Schlegelberger B, Cseh A, Noellke P, Yoshimi A, Locatelli F, Baumann I, Strahm B, Niemeyer CM, EWOG-MDS, 2016 Mar 17, Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents. Blood, DOI: 10.1182/blood-2015-09-669937 |
| Foley RW, Aworanti OM, Gorman L, McGovern B, O'Sullivan M, Smith OP, Twomey E, Gillick J, 2016 Apr, Unusual childhood presentations of abdominal non-Hodgkin's lymphoma. Pediatr Int, DOI: 10.1111/ped.12807 |
| Piccin A, Murphy C, Eakins E, Kunde J, Corvetta D, Di Pierro A, Negri G, Guido M, Sainati L, Mc Mahon C, Smith OP, Murphy W, 2015, Circulating microparticles, protein C, free protein S and endothelial vascular markers in children with sickle cell anaemia. J Extracell Vesicles, DOI: 10.3402/jev.v4.28414 |
| O'Regan N, Gegenbauer K, O'Sullivan JM, Maleki S, Brophy TM, Dalton N, Chion A, Fallon PG, Grau GE, Budde U, Smith OP, Craig AG, Preston RJ, O'Donnell JS, 2016 Mar 3, A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood, DOI: 10.1182/blood-2015-07-654921 |
| Zwaan CM, Kolb EA, Reinhardt D, Abrahamsson J, Adachi S, Aplenc R, De Bont ES, De Moerloose B, Dworzak M, Gibson BE, Hasle H, Leverger G, Locatelli F, Ragu C, Ribeiro RC, Rizzari C, Rubnitz JE, Smith OP, Sung L, Tomizawa D, van den Heuvel-Eibrink MM, Creutzig U, Kaspers GJ, 2015 Sep 20, Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia. J Clin Oncol, DOI: 10.1200/JCO.2015.62.8289 |
| O'Rafferty C, O'Regan GM, Irvine AD, Smith OP, 2015 Oct, Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon. Br J Haematol, DOI: 10.1111/bjh.13557 |
| O'Rafferty C, O'Regan GM, Irvine AD, Smith OP, 2015 Oct, Kasabach-Merritt syndrome, kaposiform haemangioendothelioma and platelet blockade. Br J Haematol, DOI: 10.1111/bjh.13558 |
| Gleeson EM, Dichiara MG, Salicio A, Quinn LM, Drakeford C, Russell SE, Walsh PT, Orbe J, Hermida J, Smith OP, O'Donnell JS, Montes R, Preston RJ, 2015 Aug 13, Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury. Blood, DOI: 10.1182/blood-2015-03-632877 |
| Niemeyer CM, Loh ML, Cseh A, Cooper T, Dvorak CC, Chan R, Xicoy B, Germing U, Kojima S, Manabe A, Dworzak M, De Moerloose B, Starý J, Smith OP, Masetti R, Catala A, Bergstraesser E, Ussowicz M, Fabri O, Baruchel A, Cavé H, Zwaan M, Locatelli F, Hasle H, van den Heuvel-Eibrink MM, Flotho C, Yoshimi A, 2015 Jan, Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia. Haematologica, DOI: 10.3324/haematol.2014.109892 |
| Piccin A, O' Marcaigh A, Mc Mahon C, Murphy C, Okafor I, Marcheselli L, Casey W, Claffey L, Smith OP, 2014 Jul, Non-activated plasma-derived PC improves amputation rate of children undergoing sepsis. Thromb Res, DOI: 10.1016/j.thromres.2014.04.019 |
| Creutzig U, Zimmermann M, Dworzak MN, Gibson B, Tamminga R, Abrahamsson J, Ha SY, Hasle H, Maschan A, Bertrand Y, Leverger G, von Neuhoff C, Razzouk B, Rizzari C, Smisek P, Smith OP, Stark B, Reinhardt D, Kaspers GL, 2014 Sep, The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01. Haematologica, DOI: 10.3324/haematol.2014.104182 |
| Langabeer SE, Smith OP, McMahon C, 2014 Mar, The JAK2 V617F mutation in pediatric myeloproliferative neoplasms: how and when? Pediatr Hematol Oncol, DOI: 10.3109/08880018.2013.869288 |
| Yoshimi A, van den Heuvel-Eibrink MM, Baumann I, Schwarz S, Simonitsch-Klupp I, de Paepe P, Campr V, Kerndrup GB, O'Sullivan M, Devito R, Leguit R, Hernandez M, Dworzak M, de Moerloose B, Stary J, Hasle H, Smith OP, Zecca M, Catala A, Schmugge M, Locatelli F, Führer M, Fischer A, Guderle A, Nöllke P, Strahm B, Niemeyer CM, 2014 Apr, Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood. Haematologica, DOI: 10.3324/haematol.2013.095786 |
| Elder PT, Cairns C, Dick A, McCallion WA, McCarthy A, Smith OP, Macartney C, 2014 Jul, A severe bleeding diathesis in a 6-year-old girl secondary to a composite diagnosis of splenic hemangiomatosis and small bowel lymphangiomatosis. J Pediatr Hematol Oncol, DOI: 10.1097/MPH.0000000000000012 |
| Leahy TR, Smith OP, Bacon CL, Storey L, Lynam P, Gavin PJ, Butler KM, O'Marcaigh AS, 2013 Oct, Does vaccine dose predict response to the monovalent pandemic H1N1 influenza a vaccine in children with acute lymphoblastic leukemia? A single-centre study. Pediatr Blood Cancer, DOI: 10.1002/pbc.24589 |
| Donnelly JC, Cooley SM, Walsh TA, Smith OP, Gillan J, McMahon C, Geary MP, 2013 Apr, Circulating pro- and anticoagulant levels in normal and complicated primigravid pregnancies and their relationship to placental pathology. J Obstet Gynaecol, DOI: 10.3109/01443615.2012.758694 |
| Krawczyk J, Maguire S, Sandys N, Kelly J, Ryan C, O'Marcaigh A, Storey L, Rooney S, Phillips C, Smith OP, 2013 Sep, In search of Pinkel's children: unravelling the biological heterogeneity of childhood acute lymphoblastic leukaemia by genotype and treatment molecular response. Ir J Med Sci, DOI: 10.1007/s11845-012-0892-8 |
| Krawczyk J, Haslam K, Lynam P, Kelly J, Storey L, O'Marcaigh A, Langabeer SE, Smith OP, 2013 Feb, No prognostic impact of P2RY8-CRLF2 fusion in intermediate cytogenetic risk childhood B-cell acute lymphoblastic leukaemia. Br J Haematol, DOI: 10.1111/bjh.12130 |
| Gleeson M, O'Marcaigh A, Cotter M, Brosnahan D, Vulliamy T, Smith OP, 2012 Dec, Retinal vasculopathy in autosomal dominant dyskeratosis congenita due to TINF2 mutation. Br J Haematol, DOI: 10.1111/bjh.12088 |
| Rao U, Piccin A, Malone A, O'Hanlon K, Breatnach F, O'Meara A, McDermott M, Butler K, O'Sullivan N, Russell J, O'Marcaigh A, Smith OP, 2013 Jun, Utility of bronchoalveolar lavage in the diagnosis of pulmonary infection in children with haematological malignancies. Ir J Med Sci, DOI: 10.1007/s11845-012-0852-3 |
| Jenkins PV, Rawley O, Smith OP, O'Donnell JS, 2012 Jun, Elevated factor VIII levels and risk of venous thrombosis. Br J Haematol, DOI: 10.1111/j.1365-2141.2012.09134.x |
| Piccin A, Murphy C, Eakins E, Kinsella A, McMahon C, Smith OP, Murphy WG, 2012 Oct, Protein C and free protein S in children with sickle cell anemia. Ann Hematol, DOI: 10.1007/s00277-012-1447-9 |
| Smith OP, 2012 Mar, Foreword for Burkitt lymphoma special issue. Br J Haematol, DOI: 10.1111/j.1365-2141.2012.09041.x |
| Alkindi S, Smith OP, Enright H, 2011 Aug, Successful Use of Alternative Anticoagulants in the Management of Heparin-induced Thrombocytopenia with Thrombotic Complications: Report of 5 cases and review of literature. Sultan Qaboos Univ Med J, DOI: 10.1111/j.1365-2141.2012.09041.x |
| Keohane C, Bacon CL, Moran B, Irvine AD, Smith OP, 2011 Feb, Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir. Pediatr Transplant, DOI: 10.1111/j.1399-3046.2010.01387.x |
| Curry S, Bacon CL, Robinson I, Capra M, Smith OP, 2010 Nov, Leukaemic alveolar rhabdomyosarcoma. Br J Haematol, DOI: 10.1111/j.1365-2141.2010.08338.x |
| Langabeer SE, Owen CJ, McCarron SL, Fitzgibbon J, Smith OP, O'Marcaigh A, Browne P, 2010 Dec, A novel RUNX1 mutation in a kindred with familial platelet disorder with propensity to acute myeloid leukaemia: male predominance of affected individuals. Eur J Haematol, DOI: 10.1111/j.1600-0609.2010.01513.x |
| Malone A, Langabeer S, O'Marcaigh A, Storey L, Bacon CL, Smith OP, 2010 Oct, A doctor(s) dilemma: ETV6-ABL1 positive acute lymphoblastic leukaemia. Br J Haematol, DOI: 10.1111/j.1365-2141.2010.08323.x |
| Piccin A, Cortelazzo S, Rovigatti U, Bourke B, Smith OP, 2010 Aug, Immunosuppressive treatments in Crohn's disease induce myelodysplasia and leukaemia. Am J Hematol, DOI: 10.1002/ajh.21755 |
| Bruneau JC, O'Marcaigh A, Smith OP, 2010 Sep, Gemtuzumab ozogamicin (Mylotarg) upregulates tissue factor expression but not secretion of inflammatory cytokines TNF-alpha or IL-8. Leuk Res, DOI: 10.1016/j.leukres.2010.04.008 |
| Sargent JT, Smith OP, 2010 May, Haematological emergencies managing hypercalcaemia in adults and children with haematological disorders. Br J Haematol, DOI: 10.1111/j.1365-2141.2010.08173.x |
| Kelly K, Storey L, O' Sullivan M, Butler K, McDermott M, Corbally M, McMahon C, Smith OP, O' Marcaigh A, 2010 Mar, Esophageal strictures during treatment for acute lymphoblastic leukemia. J Pediatr Hematol Oncol, DOI: 10.1097/MPH.0b013e3181ced25c |
| McGrath RT, McRae E, Smith OP, O'Donnell JS, 2010 Mar, Platelet von Willebrand factor--structure, function and biological importance. Br J Haematol, DOI: 10.1111/j.1365-2141.2009.08052.x |
| Bruneau JC, O'Marcaigh A, Smith OP, 2010 Jan, Pro-inflammatory and pro-coagulant properties of 6-thioguanine and 6-mercaptopurine: implications for their potential role in the development of sinusoidal obstruction syndrome. Leuk Lymphoma, DOI: 10.3109/10428190903370353 |
| Ni Ainle F, Preston RJ, Jenkins PV, Nel HJ, Johnson JA, Smith OP, White B, Fallon PG, O'Donnell JS, 2009 Aug 20, Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood, DOI: 10.1182/blood-2009-05-222109 |
| Smith OP, 2009 Mar, Thrombotic complications in children with cancer. Vnitr Lek, DOI: 10.1182/blood-2009-05-222109 |
| Piccin A, O'Marcaigh A, Deiratany S, Mc Mahon C, Smith OP, 2009 May, Severe gastrointestinal haemorrhage, first manifestation of neonatal haemophilia A. Haemophilia, DOI: 10.1111/j.1365-2516.2009.01988.x |
Please visit PubMed for more information on Owen Smith's publications
Professor Smith has a strong record of championing significant national developments in child and adolescent health in this country over the two decades. For example, he was:
The co-author of more than 350 research original articles, letters, books, book chapters and papers, Professor Smith is a Fellow of the Royal College of Paediatrics and Child Health, Royal College of Pathologists, Royal College of Physicians of Dublin, Royal College of Physicians London, Royal College of Physicians Glasgow, and Royal College of Physicians Edinburgh. He is a member of numerous associations and societies, including; the Medical Research Council Childhood Leukaemia Working Party, Children’s Oncology Group [USA], the International Berlin Frankfurt Munster Study Group for Childhood Leukaemia, the United Kingdom Children’s Cancer Group, European Working Group on paediatric aplastic anaemia and myelodysplastic syndromes. He is an international advocate for children and adolescents with rare diseases and for expanded access to expensive drugs
Professor Smith has received numerous awards throughout his career that have included; Presidents Prize of the Dublin University Biological Association in 1984 and 1985, Postgraduate Travelling Scholarship in Medicine, Sheppard Memorial Prize in Medicine and the Sir John Banks Medical in Medicine from Trinity College in 1991. He was the recipient of the Junior Chamber Ireland’s National Outstanding Young Person of the Year Award in the area of Scientific Development in 1998 and he delivered the 41st Graves Lecture and the 31st St Luke’s Lecture to the Royal Academy of Medicine in Ireland in 2001 and 2006 respectively. He was admitted to Honorary Fellowship of Trinity College Dublin in 2009 and was awarded Honorary Professorship title of Regius Professor of Physic (1637) in the School of Medicine, Trinity College Dublin in 2014.
In 2015 Professor Smith conferred honorary Commander in the Most Excellent Order of the British Empire (CBE) for his life-long work on cancer in children and adolescents by Queen Elizabeth, on the advice of the Foreign and Commonwealth Office.