Karampini E, O'Donnell JS, 2021 Jan, Correcting dominant-negative von Willebrand disease. J Thromb Haemost, DOI: 10.1111/jth.15123 |
Doherty D, Lavin M, O'Sullivan JM, Ryan K, O'Connell NM, Dougall A, Byrne M, Rafferty M, Doyle MM, Di Paola J, James P, O'Donnell JS, 2020 Dec 21, Management of Elective Procedures in Low von Willebrand factor patients in the LoVIC study. J Thromb Haemost, DOI: 10.1111/jth.15220 |
Ward SE, Curley GF, Lavin M, Fogarty H, Karampini E, McEvoy NL, Clarke J, Boylan M, Alalqam R, Worrall AP, Kelly C, de Barra E, Glavey S, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Townsend L, Mallon PW, O'Sullivan JM, O'Donnell JS, Irish COVID-19 Vasculopathy Study (ICVS) Investigators., 2020 Dec 16, Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation. Br J Haematol, DOI: 10.1111/bjh.17273 |
O'Donghaile D, Jenkins PV, McGrath RT, Preston L, Field SP, Ward SE, O'Sullivan JM, O'Donnell JS, 2020 Oct 27, Expresser phenotype determines ABO(H) blood group antigen loading on platelets and von Willebrand factor. Sci Rep, DOI: 10.1038/s41598-020-75462-2 |
O'Donovan M, Buckley C, Benson J, Roche S, McGowan M, Parkinson L, Byrne P, Rooney G, Bergin C, Walsh D, Bird R, McGroarty F, Fogarty H, Smyth E, Ahmed S, O'Donnell JS, Ryan K, O'Mahony B, Dougall A, O'Connell NM, 2020 Nov, Telehealth for delivery of haemophilia comprehensive care during the COVID-19 pandemic. Haemophilia, DOI: 10.1111/hae.14156 |
Murphy SJX, Lim ST, Hickey F, Kinsella JA, Smith DR, Tierney S, Egan B, Feeley TM, Murphy SM, Collins DR, Coughlan T, O'Neill D, Harbison JA, Madhavan P, O'Neill SM, Colgan MP, O'Donnell JS, O'Sullivan JM, Hamilton G, McCabe DJH, 2020 Sep 15, von Willebrand Factor Antigen, von Willebrand Factor Propeptide, and ADAMTS13 in Carotid Stenosis and Their Relationship with Cerebral Microemboli. Thromb Haemost, DOI: 10.1055/s-0040-1715440 |
McGonagle D, O'Donnell JS, Sharif K, Emery P, Bridgewood C, 2020 Aug, Pulmonary intravascular coagulopathy in COVID-19 pneumonia - Authors' reply. Lancet Rheumatol, DOI: 10.1016/S2665-9913(20)30174-0 |
McGonagle D, O'Donnell JS, Sharif K, Emery P, Bridgewood C, 2020 Jul, Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia. Lancet Rheumatol, DOI: 10.1016/S2665-9913(20)30121-1 |
Ward S, O'Sullivan J, O'Donnell JS, 2020 Aug 12, The relationship between ABO blood group, von Willebrand factor and primary hemostasis. Blood, DOI: 10.1182/blood.2020005843 |
O'Donnell JS, 2020 Jul 14, Low VWF: insights into pathogenesis, diagnosis, and clinical management. Blood Adv, DOI: 10.1182/bloodadvances.2020002038 |
O'Sullivan JM, Gonagle DM, Ward SE, Preston RJS, O'Donnell JS, 2020 Aug, Endothelial cells orchestrate COVID-19 coagulopathy. Lancet Haematol, DOI: 10.1016/S2352-3026(20)30215-5 |
Turecek PL, Johnsen JM, Pipe SW, O'Donnell JS, iPATH study group., 2020 Jul, Biological mechanisms underlying inter-individual variation in factor VIII clearance in haemophilia. Haemophilia, DOI: 10.1111/hae.14078 |
Moxon CA, Alhamdi Y, Storm J, Toh JMH, McGuinness D, Ko JY, Murphy G, Lane S, Taylor TE, Seydel KB, Kampondeni S, Potchen M, O'Donnell JS, O'Regan N, Wang G, García-Cardeña G, Molyneux M, Craig AG, Abrams ST, Toh CH, 2020 Jul 14, Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Adv, DOI: 10.1182/bloodadvances.2019001258 |
Gleeson EM, Rehill AM, Willis Fox O, Ni Ainle F, McDonnell CJ, Rushe HJ, McCluskey S, O'Donnell JS, Preston RJS, 2020 Jun 9, Apolipoprotein A-I enhances activated protein C cytoprotective activity. Blood Adv, DOI: 10.1182/bloodadvances.2019001316 |
McGonagle D, Plein S, O'Donnell JS, Sharif K, Bridgewood C, 2020 Jul, Increased cardiovascular mortality in African Americans with COVID-19. Lancet Respir Med, DOI: 10.1016/S2213-2600(20)30244-7 |
O'Sullivan JM, Ward S, Fogarty H, O'Donnell JS, 2020 Jul, More on 'Association between ABO blood groups and risk of SARS-CoV-2 pneumonia'. Br J Haematol, DOI: 10.1111/bjh.16845 |
Fogarty H, Townsend L, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Browne P, Bacon CL, Gaule R, Gillett A, Byrne M, Ryan K, O'Connell N, O'Sullivan JM, Conlon N, O'Donnell JS, 2020 Jun, More on COVID-19 coagulopathy in Caucasian patients. Br J Haematol, DOI: 10.1111/bjh.16791 |
Fogarty H, Doherty D, O'Donnell JS, 2020 Nov, New developments in von Willebrand disease. Br J Haematol, DOI: 10.1111/bjh.16681 |
Fogarty H, Townsend L, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Browne P, Bacon CL, Gaule R, Gillett A, Byrne M, Ryan K, O'Connell N, O'Sullivan JM, Conlon N, O'Donnell JS, 2020 Jun, COVID19 coagulopathy in Caucasian patients. Br J Haematol, DOI: 10.1111/bjh.16749 |
O'Sullivan JM, O'Donnell JS, 2020 Apr 7, Antithrombin inhibition using nanobodies to correct bleeding in hemophilia. EMBO Mol Med, DOI: 10.15252/emmm.202012143 |
Fazavana J, Brophy TM, Chion A, Cooke N, Terraube V, Cohen J, Parng C, Pittman D, Cunningham O, Lambert M, O'Donnell JS, O'Sullivan JM, 2020 Jun, Investigating the clearance of VWF A-domains using site-directed PEGylation and novel N-linked glycosylation. J Thromb Haemost, DOI: 10.1111/jth.14785 |
O'Donnell JS, Lavin M, 2019 Dec 6, Perioperative management of patients with von Willebrand disease. Hematology Am Soc Hematol Educ Program, DOI: 10.1182/hematology.2019000065 |
Ward S, O'Sullivan JM, O'Donnell JS, 2019 Jul, von Willebrand factor sialylation-A critical regulator of biological function. J Thromb Haemost, DOI: 10.1111/jth.14471 |
O'Donnell JS, O'Sullivan JM, Preston RJS, 2019 Jul, Advances in understanding the molecular mechanisms that maintain normal haemostasis. Br J Haematol, DOI: 10.1111/bjh.15872 |
Preston RJS, O'Sullivan JM, O'Donnell JS, 2019 Jul, Advances in understanding the molecular mechanisms of venous thrombosis. Br J Haematol, DOI: 10.1111/bjh.15869 |
Aguila S, Lavin M, Dalton N, Patmore S, Chion A, Trahan GD, Jones KL, Keenan C, Brophy TM, O'Connell NM, Ryan K, Byrne M, Nolan M, Patel A, Preston RJS, James P, Di Paola J, O'Sullivan JM, O'Donnell JS, 2019 Apr 4, Increased galactose expression and enhanced clearance in patients with low von Willebrand factor. Blood, DOI: 10.1182/blood-2018-09-874636 |
Aguila S, O'Donnell JS, 2019 Mar, Novel therapies for hemophilia A - the role of the von Willebrand factor chaperone. J Thromb Haemost, DOI: 10.1111/jth.14353 |
Dunne E, Qi QM, Shaqfeh ES, O'Sullivan JM, Schoen I, Ricco AJ, O'Donnell JS, Kenny D, 2019 Mar 21, Blood group alters platelet binding kinetics to von Willebrand factor and consequently platelet function. Blood, DOI: 10.1182/blood-2018-06-855528 |
Lavin M, O'Donnell JS, 2019 Feb 21, How I treat low von Willebrand factor levels. Blood, DOI: 10.1182/blood-2018-10-844936 |
Doherty D, Singleton E, Byrne M, Ryan K, O'Connell NM, O'Donnell JS, Lavin M, 2019 Feb, Missed at first Glanz: Glanzmann thrombasthenia initially misdiagnosed as Von Willebrand Disease. Transfus Apher Sci, DOI: 10.1016/j.transci.2018.11.008 |
Fogarty H, Byrne M, O’Connell NM, Ryan K, White B, O’Donnell JS, Lavin M, 2018 May 10, Acquired Factor Xiii Deficiency: An Uncommon But Easily Missed Cause Of Severe Bleeding Ir Med J, DOI: 10.1016/j.transci.2018.11.008 |
O'Sullivan JM, Ward S, Lavin M, O'Donnell JS, 2018 Oct, von Willebrand factor clearance - biological mechanisms and clinical significance. Br J Haematol, DOI: 10.1111/bjh.15565 |
Lavin M, Aguila S, Dalton N, Nolan M, Byrne M, Ryan K, White B, O'Connell NM, O'Sullivan JM, Di Paola J, James PD, O'Donnell JS, 2018 Jul 24, Significant gynecological bleeding in women with low von Willebrand factor levels. Blood Adv, DOI: 10.1182/bloodadvances.2018017418 |
Maguire CM, Lavin M, Doyle M, Byrne M, Prina-Mello A, O'Donnell JS, Volkov Y, 2018 Apr, The anticoagulant properties of cadmium telluride quantum dots. J Interdiscip Nanomed, DOI: 10.1002/jin2.35 |
Fogarty H, Doyle MM, Campbell R, Keenan C, White B, Ryan K, O'Donnell JS, Slevin J, O'Keeffe D, O'Connell NM, Lavin M, 2019 Feb, Management of combined factor V and factor VIII deficiency in pregnancy. J Obstet Gynaecol, DOI: 10.1080/01443615.2018.1448766 |
Ward SE, O'Sullivan JM, Drakeford C, Aguila S, Jondle CN, Sharma J, Fallon PG, Brophy TM, Preston RJS, Smyth P, Sheils O, Chion A, O'Donnell JS, 2018 Feb 22, A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance. Blood, DOI: 10.1182/blood-2017-06-787853 |
McDonnell CJ, Soule EE, Walsh PT, O'Donnell JS, Preston RJS, 2018 Mar, The Immunoregulatory Activities of Activated Protein C in Inflammatory Disease. Semin Thromb Hemost, DOI: 10.1055/s-0037-1608910 |
Lavin M, Ryan K, White B, Byrne M, O'Connell NM, O'Donnell JS, 2018 Jan, A role for intravenous immunoglobulin in the treatment of Acquired Von Willebrand Syndrome associated with IgM gammopathy. Haemophilia, DOI: 10.1111/hae.13374 |
O'Sullivan JM, Preston RJS, Robson T, O'Donnell JS, 2018 Mar, Emerging Roles for von Willebrand Factor in Cancer Cell Biology. Semin Thromb Hemost, DOI: 10.1055/s-0037-1607352 |
Fallon PG, Lavin M, O'Donnell JS, 2018 Jan, SIPPET: insights into factor VIII immunogenicity. J Thromb Haemost, DOI: 10.1111/jth.13886 |
Lavin M, Aguila S, Schneppenheim S, Dalton N, Jones KL, O'Sullivan JM, O'Connell NM, Ryan K, White B, Byrne M, Rafferty M, Doyle MM, Nolan M, Preston RJS, Budde U, James P, Di Paola J, O'Donnell JS, 2017 Nov 23, Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels. Blood, DOI: 10.1182/blood-2017-05-786699 |
Drakeford C, O'Donnell JS, 2017 Sep, Targeting von Willebrand Factor-Mediated Inflammation. Arterioscler Thromb Vasc Biol, DOI: 10.1161/ATVBAHA.117.309817 |
Gleeson EM, McDonnell CJ, Soule EE, Willis Fox O, Rushe H, Rehill A, Smith OP, O'Donnell JS, Preston RJS, 2017 Nov, A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective protease-activated receptor 1 signaling. J Thromb Haemost, DOI: 10.1111/jth.13807 |
Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Egan B, Feeley TM, Coughlan T, Collins DR, O'Neill D, Murphy S, Lim SJ, Murphy RP, McCabe D, 2017 Apr 15, Profile of von Willebrand factor antigen and von Willebrand factor propeptide in an overall TIA and ischaemic stroke population and amongst subtypes. J Neurol Sci, DOI: 10.1016/j.jns.2017.02.045 |
Brophy TM, Ward SE, McGimsey TR, Schneppenheim S, Drakeford C, O'Sullivan JM, Chion A, Budde U, O'Donnell JS, 2017 May, Plasmin Cleaves Von Willebrand Factor at K1491-R1492 in the A1-A2 Linker Region in a Shear- and Glycan-Dependent Manner In Vitro. Arterioscler Thromb Vasc Biol, DOI: 10.1161/ATVBAHA.116.308524 |
Lavin M, O'Donnell JS, 2016 Dec 2, New treatment approaches to von Willebrand disease. Hematology Am Soc Hematol Educ Program, DOI: 10.1182/asheducation-2016.1.683 |
O'Sullivan JM, Aguila S, McRae E, Ward SE, Rawley O, Fallon PG, Brophy TM, Preston RJ, Brady L, Sheils O, Chion A, O'Donnell JS, 2016 Dec, N-linked glycan truncation causes enhanced clearance of plasma-derived von Willebrand factor. J Thromb Haemost, DOI: 10.1111/jth.13537 |
Chion A, O'Sullivan JM, Drakeford C, Bergsson G, Dalton N, Aguila S, Ward S, Fallon PG, Brophy TM, Preston RJ, Brady L, Sheils O, Laffan M, McKinnon TA, O'Donnell JS, 2016 Oct 13, N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance. Blood, DOI: 10.1182/blood-2016-04-709436 |
Lakshmanan RS, Efremov V, O'Donnell JS, Killard AJ, 2016 Sep, Measurement of the viscoelastic properties of blood plasma clot formation in response to tissue factor concentration-dependent activation. Anal Bioanal Chem, DOI: 10.1007/s00216-016-9689-3 |
O'Sullivan JM, Jenkins PV, Rawley O, Gegenbauer K, Chion A, Lavin M, Byrne B, O'Kennedy R, Preston RJ, Brophy TM, O'Donnell JS, 2016 May, Galectin-1 and Galectin-3 Constitute Novel-Binding Partners for Factor VIII. Arterioscler Thromb Vasc Biol, DOI: 10.1161/ATVBAHA.115.306915 |
Lavin M, Brophy TM, Rawley O, O'Sullivan JM, Hayden PJ, Browne PV, Ryan K, O'Connell N, O'Donnell JS, 2016 Jun, Lenalidomide as a novel treatment for refractory acquired von Willebrand syndrome associated with monoclonal gammopathy. J Thromb Haemost, DOI: 10.1111/jth.13317 |
O'Sullivan JM, Preston RJ, O'Regan N, O'Donnell JS, 2016 May 12, Emerging roles for hemostatic dysfunction in malaria pathogenesis. Blood, DOI: 10.1182/blood-2015-11-636464 |
O'Regan N, Moxon C, Gegenbauer K, O'Sullivan JM, Chion A, Smith OP, Preston RJ, Brophy TM, Craig AG, O'Donnell JS, 2016 Apr, Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria. Thromb Haemost, DOI: 10.1160/TH15-10-0796 |
Quinn LM, Drakeford C, O'Donnell JS, Preston RJ, 2015 Aug, Engineering activated protein C to maximize therapeutic efficacy. Biochem Soc Trans, DOI: 10.1042/BST20140312 |
O'Regan N, Gegenbauer K, O'Sullivan JM, Maleki S, Brophy TM, Dalton N, Chion A, Fallon PG, Grau GE, Budde U, Smith OP, Craig AG, Preston RJ, O'Donnell JS, 2016 Mar 3, A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood, DOI: 10.1182/blood-2015-07-654921 |
Lavin M, Jenkins PV, Keenan C, White B, Betts DR, O'Donnell JS, O'Connell NM, 2016 Jan, X-linked moyamoya syndrome associated with severe haemophilia A. Haemophilia, DOI: 10.1111/hae.12806 |
Lavin M, Jenkins PV, Healy ML, Byrne M, O'Connell NM, O'Donnell JS, 2015 Nov, Age-related factor IX correction in symptomatic female carriers with haemophilia B Leyden. Haemophilia, DOI: 10.1111/hae.12761 |
Lavin M, Kavanagh J, Beddy P, O'Connell NM, O'Donnell JS, 2016 Jan, Recurrent lower limb venous thrombosis associated with a congenitally absent infrarenal inferior vena cava. QJM, DOI: 10.1093/qjmed/hcv123 |
Gleeson EM, Dichiara MG, Salicio A, Quinn LM, Drakeford C, Russell SE, Walsh PT, Orbe J, Hermida J, Smith OP, O'Donnell JS, Montes R, Preston RJ, 2015 Aug 13, Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury. Blood, DOI: 10.1182/blood-2015-03-632877 |