Eleanor Molloy


Eleanor Molloy

Professor of Paediatrics & Child Health, TCD

Eleanor Molloy is the Professor and Chair of Paediatrics at Trinity College Dublin and a Consultant Neonatologist & Paediatrician at the Coombe Women and Infant’s University Hospital, the National Children’s Hospital, Tallaght, and Children’s Health Ireland at Crumlin.

Prof. Molloy’s research group aims to delineate perinatal and early neonatal inflammatory responses in health and disease. They have established longitudinal cohorts of infants with neonatal encephalopathy and preterm infants as well as neonatal controls in order to explore the role of early inflammatory changes and developmental outcomes.

Eleanor Molloy

Professor of Paediatrics & Child Health, TCD

Dr. Lynne Kelly
Position: Research Fellow
Kellyl37@tcd.ie

Role:
Post doctoral researcher in GEMINI and research coordinator of the Paediatrics research lab in TTMI, St James’ Hospital.

Dr. Emer Ryan
Position: PhD Researcher

Role:
PhD in Paediatric Outcomes and Serum biomarker Panel in acute traumatic brain injury /concussion to severe traumatic brain injury .

Dr. Matthew McGovern
Position: PhD Researcher

Role:
PhD in Gender and Neonatal Inflammation in preterm outcomes.

Dr. Tim Hurley
Position: PhD Researcher

Role:
PhD in Circadian Rhythm Alterations and outcome in neonatal Encephalopathy.

Dr. Saima Aslam
Position: PhD Researcher

Role:
PhD in Understanding systemic Inflammation& immunomodulation in neontatal brain injury .

Dr. Murwan Omer
Position: PhD Researcher

Role:
PhD in Preterm Infection and Systemic inflammation and neonatal outcomes.

Dr. Niamh Lagan
Position: PhD Researcher

Role:
PhD in Down syndrome, neurodevelopment and multiorgan outcomes.

Dr. John Allen
Position: PhD Researcher

Role:
PhD in Severe Neurological Impairment and children with medical complexity.

NIMBUS: Neonatal Inflammation and Multiorgan dysfunction and Brain injUry reSearch group

Neonatal brain injury (NBI) has a heterogenous aetiology with a high economic and social burden. Neonatal encephalopathy describes the babies who require resuscitation at birth and have an abnormal neurological examination. It remains difficult to predict their developmental outcome. Enhanced inflammatory responses are seen in affected infants and correlate with outcomes. Multiorgan dysfunction is common with renal, hepatic, cardiac and haematological abnormalities.We aim to correlate these inflammatory responses with clinical, neurodevelopmental and MRI outcomes to establish biomarkers of brain injury in neonates. This research may allow early recognition of brain injury prior to MRI (Day 5-7) so that new therapies as adjuvants to therapeutic hypothermia can be initiated as soon as possible after birth.

UNICORN: Underlying mechanisms in Neonatal Immune metaboliC dysregulatiOn and bRain Injury.

: Persistent systemic inflammation has been implicated in neonatal brain injury and identifying novel inflammatory biomarker combinations will help to determine the aetiology of NE and develop new adjunctive therapies. We have shown that immune cell ROS are produced at abnormally high levels in infants with severe NE and increase over the first week of life despite therapeutic hypothermia (TH) therapy. Babies with NE and age-matched controls will have inflammatory phenotyping in terms of immune cell activation and cytokine production to assess t immune dysregulation. Detailed neuroimaging using MRI/MRS (1.5T & 3.0T) and neurological outcome will be correlated with these results in order to assist with improved prognostic biomarker development. We will examine cellular metabolism and mitochondrial function in samples from infants with NE in comparison to healthy neonates with a view to identifying altered pathways that could be targeted by potential adjunctive therapies.

PROSPER: PaediatRic Outcomes and Serum biomarker Panel in acutE traumatic bRain injury /concussion to severe traumatic brain injury

Traumatic brain injury (TBI) is more common in childhood and adolescence than at any other time of life and is one of the most common causesof neurological morbidity and includes concussion. Post concussion syndrome (PCS) combines clinical, cognitive and behavioral symptoms and occurs in one in sevenschool children sustaining an TBI for three months or longerand is associated with persistent inflammation. At present there are no evidence-based clinical guidelines or accurate early tests to predict PCS in children. We aim to prospectively evaluate novel clinical and biochemical markers neurocognitive function at presentation inthe Emergency department and at 6 weeks in children presenting with TBI.

DISCO: Down syndrome Inflammation and Systemic multiorgan outCOmes

Down syndrome is associated with increased incidence of infections in childhood and other inflammatory conditions such as rheumatoid arthritis and Alzheimers disease have an earlier onset. Modulation of inflammatory signalling during infection may improve developmental outcomes. We will evaluate detailed clinical multiorgan outcomes and correlate with detailed developmental outcomes including audiology, Bayley’s developmental scales (BSID III) and WIPPSI and explore the effects of organ dysfunction on outcome. We will examine pro and anti-inflammatory cytokine responses and evaluate the innate inflammatory cell phenotype and activation of the inflammasome. This research will improve the understanding of the systemic inflammatory response in children with Down Syndrome and the potential for newer adjunctive therapies. In addition these immune markers may assist in prognosis of multi-organ outcomes in children with DS.

CRADLE: Circadian Rhythm Alterations anD outcome in neonatal Encephalopathy

Changes in circadian rhythm are common in many illnesses including neonatal brain injury and neonatal encephalopathy (NE). NE is associated with persistent abnormal systemic inflammatory responses that may be amenable to immunomodulation as an adjunct to therapeutic hypothermia. Alterations in circadian rhythm affect immune function and are associated with changes in melatonin, which has anti-inflammatory properties. Understanding the role of the circadian rhythm in neonatal brain injury and inflammation may lead to simple therapeutic measures such as decreasing the duration duration of light exposure to increase endogenous melatonin production. Therefore, we wish to investigate whether alteration of the circadian rhythm in babies with NE decrease inflammation and improve outcome?

GENIE: GEnder and neonatal Inflammation in prEterm outcomes

From infancy to old age,males have poorer disease outcomes compared to females.Preterm infants display a marked gender dimorphism as regards outcome and mortality especially at the borders of viability.We will explore the role of infection and gender in preterm infants in a large prospective cohort examining sex steroid hormones, infection, inflammation and neonatal multiorgan outcomes including brain injury. We will also translate the immune results to include possible new immunomodulatory therapies exploring the roles of estradiol, testoterone and glucocorticoids.

NEBULA: Understanding systemic InfLAmmation & immunomodulation

Neonatal brain injury has multifactorial etiology and causes significant neurological morbidity such as cerebral palsy. Therapeutic hypothermia is the only treatment available in term infants with neonatal encephalopathy (altered neurological function). Activated leucocytes, infection and persistent inflammation have been implicated in the pathogenesis of brain injury and cerebral palsy. Circadian rhythm plays a key role in innate immune responses and melatonin is an essential regulator. Melatonin has been shown to improve outcomes in combination with hypothermia in animal models of neonatal brain injury. Hypoxia-inducible factor (HIF) 1 alpha is a key transcriptional factor in the hypoxic response and is associated with persistent inflammation.We will examine circadian Rhythm and HIF-1alpha in neonatal NE and Control samples. This research will improve the understanding of the systemic inflammatory response in infants with brain injury and the potential for therapies such asmelatonin in addition to hypothermia.

PRISM: PReterm Infection and SysteMic inflammation and neonatal outcomes

Despite rapid progress in neonatal intensive care over the past decades, neonatal mortality from sepsis remains unacceptably highand morbidity includes brain injury and developmental delay. Systemic inflammation related to sepsis has been implicated in many common neonatal complications such as brain, lung, or gastrointestinal injuryespecially in preterm infants. Modulation of inflammatory signalling during sepsis may improve survival in preterm infants and prevent related neurodevelopmental complications. This research will improve the understanding of the systemic inflammatory response in preterm infants and the potential for newer adjunctive therapies. In addition these immune markers will assist in prognosis of multi-organ outcomes in preterm infants.

SERENITY: SEveRE Neurological Impairment and children with medical complexiTY

Severe Neurological Impairment (SNI) is a term that has been used to describe a global impairment of the nervous system. This group of children, who have unique challenges, could be considered a sub-group of those with more general medical complexity. However, there is no internationally agreed definition of severe neurological impairment and, therefore, a paucity of literature on its prevalence and medical and social consequences. This information is vital for future resource planning so we can provide the very best care for this vulnerable group of individuals. Objectives 1.To create a consensus definition of SNI 2.To quantify medical complexity in this group 3.To assess wellbeing in the families of children with SNI

The list of publications below is automatically derived from MEDLINE/PubMed. As a result, there may be incorrect or missing publications.

Sweetman DU, Strickland T, Isweisi E, Kelly L, Slevin MT, Donoghue V, Meehan J, Boylan G, Murphy JFA, El-Khuffash A, Molloy EJ, 2021 Sep 16, Multi-organ dysfunction scoring in neonatal encephalopathy (MODE Score) and neurodevelopmental outcomes. Acta Paediatr, DOI: 10.1111/apa.16111
Ryan E, Kelly L, Stacey C, Duff E, Huggard D, Leonard A, Boran G, McCollum D, Doherty D, Bolger T, Molloy EJ, 2021 Aug 30, Traumatic Brain Injury in Children: Glial fibrillary Acidic Protein and Clinical Outcomes. Pediatr Emerg Care, DOI: 10.1097/PEC.0000000000002527
Zakharchenko L, El-Khuffash A, Molloy EJ, Breatnach C, Franklin O, 2021 Aug 31, Peri-operative myocardial performance in infants with Down syndrome undergoing CHD repair. Cardiol Young, DOI: 10.1017/S1047951121003449
Allen J, Zareen Z, Doyle S, Whitla L, Afzal Z, Stack M, Franklin O, Green A, James A, Leahy TR, Quinn S, Elnazir B, Russell J, Paran S, Kiely P, Roche EF, McDonnell C, Baker L, Hensey O, Gibson L, Kelly S, McDonald D, Molloy EJ, 2021, Multi-Organ Dysfunction in Cerebral Palsy. Front Pediatr, DOI: 10.3389/fped.2021.668544
Sandoval Karamian AG, Mercimek-Andrews S, Mohammad K, Molloy EJ, Chang T, Chau V, Murray DM, Wusthoff CJ, Newborn Brain Society Guidelines and Publications Committee., 2021 Aug 4, Neonatal encephalopathy: Etiologies other than hypoxic-ischemic encephalopathy. Semin Fetal Neonatal Med, DOI: 10.1016/j.siny.2021.101272
Huggard D, Kelly L, Worrall A, Gallagher E, Fallah L, Yoo LL, McGrane F, Lagan N, Roche E, Balfe J, Doherty DG, Molloy EJ, 2021 Aug 16, Melatonin as an immunomodulator in children with Down syndrome. Pediatr Res, DOI: 10.1038/s41390-021-01611-6
Isweisi E, Moore CM, Hurley T, Sola-Visner M, McCallion N, Ainle FN, Zareen Z, Sweetman DU, Curley AE, Molloy EJ, Newborn Brain Society Guidelines and Publications Committee., 2021 Jul 22, Haematological issues in neonates with neonatal encephalopathy treated with hypothermia. Semin Fetal Neonatal Med, DOI: 10.1016/j.siny.2021.101270
Wong SK, Chim M, Allen J, Butler A, Tyrrell J, Hurley T, McGovern M, Omer M, Lagan N, Meehan J, Cummins EP, Molloy EJ, 2021 Jul 6, Carbon dioxide levels in neonates: what are safe parameters? Pediatr Res, DOI: 10.1038/s41390-021-01473-y
Ní Bhroin M, Molloy EJ, Bokde ALW, 2021 Jul, Relationship between resting-state fMRI functional connectivity with motor and language outcome after perinatal brain injury - A systematic review. Eur J Paediatr Neurol, DOI: 10.1016/j.ejpn.2021.05.007
Taher NAB, Kelly LA, Al-Harbi AI, O'Dea MI, Zareen Z, Ryan E, Molloy EJ, Doherty DG, 2021 Jul 15, Altered distributions and functions of natural killer T cells and γδ T cells in neonates with neonatal encephalopathy, in school-age children at follow-up, and in children with cerebral palsy. J Neuroimmunol, DOI: 10.1016/j.jneuroim.2021.577597
Zareen Z, Allen J, Kelly LA, McDonald D, Sweetman D, Molloy EJ, 2021 Aug, An observational study of sleep in childhood post-neonatal encephalopathy. Acta Paediatr, DOI: 10.1111/apa.15902
McKenna E, Mhaonaigh AU, Wubben R, Dwivedi A, Hurley T, Kelly LA, Stevenson NJ, Little MA, Molloy EJ, 2021, Neutrophils: Need for Standardized Nomenclature. Front Immunol, DOI: 10.3389/fimmu.2021.602963
Fleming PF, Gale C, Molloy EJ, Faust SN, Costeloe K, Juszczak E, Roehr CC, 2021 Aug, Paediatric research in the times of COVID-19. Pediatr Res, DOI: 10.1038/s41390-021-01479-6
Klingenberg C, Tembulkar SK, Lavizzari A, Roehr CC, Ehret DEY, Vain NE, Mariani GL, Erdeve O, Lara-Diaz VJ, Velaphi S, Cheong HK, Bisht SS, Waheed KAI, Stevenson AG, Al-Kafi N, Roue JM, Barrero-Castillero A, Molloy EJ, Zupancic JAF, Profit J, International Neonatal COVID-19 Consortium., 2021 May, COVID-19 preparedness-a survey among neonatal care providers in low- and middle-income countries. J Perinatol, DOI: 10.1038/s41372-021-01019-4
Kelly LA, O'Dea MI, Zareen Z, Melo AM, McKenna E, Strickland T, McEneaney V, Donoghue V, Boylan G, Sweetman D, Butler J, Vavasseur C, Miletin J, El-Khuffash AF, O'Neill LAJ, O'Leary JJ, Molloy EJ, 2021 Jul, Altered inflammasome activation in neonatal encephalopathy persists in childhood. Clin Exp Immunol, DOI: 10.1111/cei.13598
O'Dea MI, Kelly L, McKenna E, Melo AM, Ni Bhroin M, Hurley T, Byrne AT, Colleran G, Vavasseur C, El-Khuffash A, Miletin J, Murphy J, Hickey F, Molloy EJ, 2020, Dysregulated Monocyte and Neutrophil Functional Phenotype in Infants With Neonatal Encephalopathy Requiring Therapeutic Hypothermia. Front Pediatr, DOI: 10.3389/fped.2020.598724
Sweetman DU, Strickland T, Melo AM, Kelly LA, Onwuneme C, Watson WR, Murphy JFA, Slevin M, Donoghue V, O'Neill A, Molloy EJ, 2020, Neonatal Encephalopathy Is Associated With Altered IL-8 and GM-CSF Which Correlates With Outcomes. Front Pediatr, DOI: 10.3389/fped.2020.556216
Quirke FA, Healy P, Bhraonáin EN, Daly M, Biesty L, Hurley T, Walker K, Meher S, Haas DM, Bloomfield FH, Kirkham JJ, Molloy EJ, Devane D, 2021 Feb 15, Multi-Round compared to Real-Time Delphi for consensus in core outcome set (COS) development: a randomised trial. Trials, DOI: 10.1186/s13063-021-05074-2
Quirke FA, Healy P, Bhraonáin EN, Daly M, Biesty L, Hurley T, Walker K, Meher S, Haas DM, Bloomfield FH, Kirkham JJ, Molloy EJ, Devane D, 2021 Feb 8, COHESION: core outcomes in neonatal encephalopathy (protocol). Trials, DOI: 10.1186/s13063-021-05030-0
Dibble M, Ang JZ, Mariga L, Molloy EJ, Bokde ALW, 2021 May, Diffusion Tensor Imaging in Very Preterm, Moderate-Late Preterm and Term-Born Neonates: A Systematic Review. J Pediatr, DOI: 10.1016/j.jpeds.2021.01.008
Twohig A, Murphy JF, McCarthy A, Segurado R, Underdown A, Smyke A, McNicholas F, Molloy EJ, 2021 Jan 11, The preterm infant-parent programme for attachment-PIPPA Study: a randomised controlled trial. Pediatr Res, DOI: 10.1038/s41390-020-01262-z
Donnelly JMT, Horan M, Segurado R, Mooney EE, French S, Molloy EJ, McAuliffe FM, 2020 Nov 22, Sexual dimorphism and the placenta - results from the ROLO kids study. J Matern Fetal Neonatal Med, DOI: 10.1080/14767058.2020.1849097
Zareen Z, Strickland T, Fallah L, McEneaney V, Kelly L, McDonald D, Molloy EJ, 2021 Apr, Cytokine dysregulation in children with cerebral palsy. Dev Med Child Neurol, DOI: 10.1111/dmcn.14724
Molloy EJ, Bearer CF, 2021 Jul, Translational research is all-encompassing and lets everyone be a researcher. Pediatr Res, DOI: 10.1038/s41390-020-01225-4
Molloy EJ, Wynn JL, Bliss J, Koenig JM, Keij FM, McGovern M, Kuester H, Turner MA, Giannoni E, Mazela J, Degtyareva M, Strunk T, Simons SHP, Janota J, Plotz FB, van den Hoogen A, de Boode W, Schlapbach LJ, Reiss IKM, Infection, Inflammation, Immunology and Immunisation (I4) section of the ESPR., 2021 Jul, Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatr Res, DOI: 10.1038/s41390-020-01221-8
Omer M, Melo AM, Kelly L, Mac Dermott EJ, Leahy TR, Killeen O, Saugstad OD, Savani RC, Molloy EJ, 2020, Emerging Role of the NLRP3 Inflammasome and Interleukin-1β in Neonates. Neonatology, DOI: 10.1159/000507584
Del Rosario C, Slevin M, Molloy EJ, Quigley J, Nixon E, 2021 Apr, How to use the Bayley Scales of Infant and Toddler Development. Arch Dis Child Educ Pract Ed, DOI: 10.1136/archdischild-2020-319063
Whitla L, Devins M, Molloy EJ, Twomey M, O'Reilly M, Balfe J, 2020 Jun 11, Children's Palliative Care; the identified Learning Needs of Paediatricians. Ir Med J, DOI: 10.1136/archdischild-2020-319063
Ryan E, Bolger T, Barrett MJ, Blackburn C, Okafor I, McNamara R, Molloy EJ, 2020 Jun 11, Paediatric Head Injury and Traumatic Brain Injury. Ir Med J, DOI: 10.1136/archdischild-2020-319063
Molloy EJ, Strunk T, 2021 Jan 1, Role of C-Reactive Protein for Late-Onset Neonatal Sepsis. JAMA Pediatr, DOI: 10.1001/jamapediatrics.2020.2126
Molloy EJ, Lavizzari A, Klingenberg C, Profit J, Zupancic JAF, Davis AS, Mosca F, Bearer CF, Roehr CC, International Neonatal COVID-19 Consortium., 2021 Apr, Neonates in the COVID-19 pandemic. Pediatr Res, DOI: 10.1038/s41390-020-1096-y
Molloy EJ, Cummins EP, 2021 Apr, Carbon dioxide as a drug in neonatology. Pediatr Res, DOI: 10.1038/s41390-020-1051-y
Doughty C, O'Driscoll DN, Smith S, O'Currain E, Grant T, O'Hare FM, Culliton M, Watson RWG, O'Neill A, Molloy EJ, 2020 Jul 16, Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in neonatal sepsis. J Matern Fetal Neonatal Med, DOI: 10.1080/14767058.2020.1786520
Woods I, Black A, Molloy EJ, Jockenhoevel S, Flanagan TC, 2020 Sep, Fabrication of blood-derived elastogenic vascular grafts using electrospun fibrinogen and polycaprolactone composite scaffolds for paediatric applications. J Tissue Eng Regen Med, DOI: 10.1002/term.3100
Lavizzari A, Klingenberg C, Profit J, Zupancic JAF, Davis AS, Mosca F, Molloy EJ, Roehr CC, International Neonatal COVID-19 Consortium., 2021 Mar, International comparison of guidelines for managing neonates at the early phase of the SARS-CoV-2 pandemic. Pediatr Res, DOI: 10.1038/s41390-020-0976-5
O'Dea M, Sweetman D, Bonifacio SL, El-Dib M, Austin T, Molloy EJ, 2020, Management of Multi Organ Dysfunction in Neonatal Encephalopathy. Front Pediatr, DOI: 10.3389/fped.2020.00239
Molloy EJ, Bearer CF, 2020 Oct, When research goes wrong: the importance of clinical trials methodology. Pediatr Res, DOI: 10.1038/s41390-020-0984-5
Molloy EJ, 2021 Feb, The Doctor's Dilemma: lessons from GB Shaw in a modern pandemic COVID-19. Pediatr Res, DOI: 10.1038/s41390-020-0927-1
Sweetman DU, Kelly L, Hurley T, Onwuneme C, Watson RWG, Murphy JFA, Slevin M, Donoghue V, Molloy EJ, 2020 Nov, Troponin T correlates with MRI results in neonatal encephalopathy. Acta Paediatr, DOI: 10.1111/apa.15255
Molloy EJ, Murphy N, 2020 Apr 3, Vitamin D, Covid-19 and Children. Ir Med J, DOI: 10.1111/apa.15255
Molloy EJ, Bearer CF, 2020 Sep, COVID-19 in children and altered inflammatory responses. Pediatr Res, DOI: 10.1038/s41390-020-0881-y
Zareen Z, Strickland T, Eneaney VM, Kelly LA, McDonald D, Sweetman D, Molloy EJ, 2020 Mar 30, Cytokine dysregulation persists in childhood post Neonatal Encephalopathy. BMC Neurol, DOI: 10.1186/s12883-020-01656-w
Molloy EJ, Wynn JL, Bliss J, Koenig JM, Keij FM, McGovern M, Kuester H, Turner MA, Giannoni E, Mazela J, Degtyareva M, Strunk T, Simons SHP, Janota J, Plotz FB, van den Hoogen A, de Boode W, Schlapbach LJ, Reiss IKM, on behalf of the Infection, Inflammation, Immunology and Immunisation (I4) section of the ESPR., 2020 Jul, Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatr Res, DOI: 10.1038/s41390-020-0850-5
Huggard D, Doherty DG, Molloy EJ, 2020, Immune Dysregulation in Children With Down Syndrome. Front Pediatr, DOI: 10.3389/fped.2020.00073
McGovern M, Giannoni E, Kuester H, Turner MA, van den Hoogen A, Bliss JM, Koenig JM, Keij FM, Mazela J, Finnegan R, Degtyareva M, Simons SHP, de Boode WP, Strunk T, Reiss IKM, Wynn JL, Molloy EJ, Infection, Inflammation, Immunology and Immunisation (I4) section of the ESPR., 2020 Jul, Challenges in developing a consensus definition of neonatal sepsis. Pediatr Res, DOI: 10.1038/s41390-020-0785-x
Lagan N, Huggard D, Mc Grane F, Leahy TR, Franklin O, Roche E, Webb D, O' Marcaigh A, Cox D, El-Khuffash A, Greally P, Balfe J, Molloy EJ, 2020 Jun, Multiorgan involvement and management in children with Down syndrome. Acta Paediatr, DOI: 10.1111/apa.15153
Dibble M, O'Dea MI, Hurley T, Byrne A, Colleran G, Molloy EJ, Bokde ALW, 2020 Sep, Diffusion tensor imaging in neonatal encephalopathy: a systematic review. Arch Dis Child Fetal Neonatal Ed, DOI: 10.1136/archdischild-2019-318025
Huggard D, Kelly L, Ryan E, McGrane F, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Doherty DG, Molloy EJ, 2020 Mar, Increased systemic inflammation in children with Down syndrome. Cytokine, DOI: 10.1016/j.cyto.2019.154938
Ui Mhaonaigh A, Coughlan AM, Dwivedi A, Hartnett J, Cabral J, Moran B, Brennan K, Doyle SL, Hughes K, Lucey R, Floudas A, Fearon U, McGrath S, Cormican S, De Bhailis A, Molloy EJ, Brady G, Little MA, 2019, Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies. Front Immunol, DOI: 10.3389/fimmu.2019.02603
Sweetman D, Kelly LA, Zareen Z, Nolan B, Murphy J, Boylan G, Donoghue V, Molloy EJ, 2019, Coagulation Profiles Are Associated With Early Clinical Outcomes in Neonatal Encephalopathy. Front Pediatr, DOI: 10.3389/fped.2019.00399
Eliwan HO, Watson WRG, Regan I, Philbin B, O'Hare FM, Strickland T, O'Neill A, O'Rourke M, Blanco A, Healy M, Nolan B, Smith O, Molloy EJ, 2019, Pediatric Intensive Care: Immunomodulation With Activated Protein C ex vivo. Front Pediatr, DOI: 10.3389/fped.2019.00386
Huggard D, Koay WJ, Kelly L, McGrane F, Ryan E, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno-Oliveira A, Melo AM, Doherty DG, Molloy EJ, 2019, Altered Toll-Like Receptor Signalling in Children with Down Syndrome. Mediators Inflamm, DOI: 10.1155/2019/4068734
Ryan E, Eves D, Menon PJ, Alnafisee S, Mooney EE, Downey P, Culliton M, Murphy JFA, Vavasseur C, Molloy EJ, 2020 Apr, Histological chorioamnionitis is predicted by early infant C-reactive protein in preterm infants and correlates with neonatal outcomes. Acta Paediatr, DOI: 10.1111/apa.15038
Bearer CF, Chalak L, Fuentes-Afflick E, Molloy EJ, 2020 Jan, The rewards of peer-reviewing. Pediatr Res, DOI: 10.1038/s41390-019-0573-7
Molloy EJ, 2019 Dec, Dr Janusz Korczak: paediatrician, children's advocate and hero. Pediatr Res, DOI: 10.1038/s41390-019-0495-4
O'Leary N, Jairaj C, Molloy EJ, McAuliffe FM, Nixon E, O'Keane V, 2019 Jul, Antenatal depression and the impact on infant cognitive, language and motor development at six and twelve months postpartum. Early Hum Dev, DOI: 10.1016/j.earlhumdev.2019.05.021
Aslam S, Strickland T, Molloy EJ, 2019, Neonatal Encephalopathy: Need for Recognition of Multiple Etiologies for Optimal Management. Front Pediatr, DOI: 10.3389/fped.2019.00142
Molloy EJ, Bearer CF, 2019 Aug, Insights in Pediatric Research. Pediatr Res, DOI: 10.1038/s41390-019-0394-8
Brennan K, O'Leary BD, Mc Laughlin D, Kinlen D, Molloy EJ, Cody D, Paran S, McAuliffe FM, Hogan AE, Doyle SL, 2019 Jul, Nucleic acid cytokine responses in obese children and infants of obese mothers. Cytokine, DOI: 10.1016/j.cyto.2019.03.015

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