Declan Cody


Declan Cody

Consultant Pediatric Endocrinologist

Professor Cody is a Consultant Endocrinologist in Our Lady’s Children’s Hospital, Crumlin and a Principal Investigator in the Childhood Obesity Consortium, an NCRC funded research programme focused on the study of chronic inflammation and innate immune dysregulation in childhood and adolescent obesity.

Declan Cody

Consultant Pediatric Endocrinologist

Dr David Kinlen
Position: Pediatric SpR and M.D candidate

Role:
David is a paediatric endocrinologist and M.D candidate. He is currently investigating the role of IL-17+ MAIT cells in the development of insulin resistance.

Investigating the impact of childhood obesity on innate immune cell function and metabolism, and their modulation by Metformin and Glucagon like peptide-1

Currently there is no protocol for the targeting inflammation in childhood obesity, allowing the development of co-morbid diseases to go unchecked into adulthood. We aim to investigate the impact of the anti-diabetic agent metformin (in vivo) and the weight loss and immunomodulatory agent Glucagon Like Peptide-1 (in vitro) on obesity driven inflammation in children. This will generate an expanded evidence base for potential therapeutic use in childhood obesity.



The list of publications below is automatically derived from MEDLINE/PubMed. As a result, there may be incorrect or missing publications.

McGrath N, Hawkes CP, McDonnell CM, Cody D, O'Connell SM, Mayne PD, Murphy NP, 2018 Oct, Incidence of Congenital Hypothyroidism Over 37 Years in Ireland. Pediatrics, DOI: 10.1542/peds.2018-1199
Svensson J, Schwandt A, Pacaud D, Beltrand J, Birkebaek NH, Cardona-Hernandez R, Casteels K, Castro S, Cherubini V, Cody D, Fisch N, Hasnani D, Kordonouri O, Kosteria I, Luczay A, Pundziute-Lyckå A, Maffeis C, Piccini B, Luxmi P, Sumnik Z, de Beaufort C, 2018 Dec, The influence of treatment, age at onset, and metabolic control on height in children and adolescents with type 1 diabetes-A SWEET collaborative study. Pediatr Diabetes, DOI: 10.1111/pedi.12751
Yap KL, Johnson AEK, Fischer D, Kandikatla P, Deml J, Nelakuditi V, Halbach S, Jeha GS, Burrage LC, Bodamer O, Benavides VC, Lewis AM, Ellard S, Shah P, Cody D, Diaz A, Devarajan A, Truong L, Greeley SAW, De Leon DD, Edmondson AC, Das S, Thornton P, Waggoner D, Del Gaudio D, 2018 Aug 11, Correction: "Congenital hyperinsulinism as the presenting feature of Kabuki syndrome: clinical and molecular characterization of 10 affected individuals". Genet Med, DOI: 10.1038/s41436-018-0126-1
Yap KL, Johnson AEK, Fischer D, Kandikatla P, Deml J, Nelakuditi V, Halbach S, Jeha GS, Burrage LC, Bodamer O, Benavides VC, Lewis AM, Ellard S, Shah P, Cody D, Diaz A, Devarajan A, Truong L, Greeley SAW, De Leó-Crutchlow DD, Edmondson AC, Das S, Thornton P, Waggoner D, Del Gaudio D, 2018 Jun 15, Congenital hyperinsulinism as the presenting feature of Kabuki syndrome: clinical and molecular characterization of 10 affected individuals. Genet Med, DOI: 10.1038/s41436-018-0013-9
Lynch SA, Crushell E, Lambert DM, Byrne N, Gorman K, King MD, Green A, O'Sullivan S, Browne F, Hughes J, Knerr I, Monavari AA, Cotter M, McConnell VPM, Kerr B, Jones SA, Keenan C, Murphy N, Cody D, Ennis S, Turner J, Irvine AD, Casey J, 2018 Apr, Catalogue of inherited disorders found among the Irish Traveller population. J Med Genet, DOI: 10.1136/jmedgenet-2017-104974
Tobin LM, Mavinkurve M, Carolan E, Kinlen D, O'Brien EC, Little MA, Finlay DK, Cody D, Hogan AE, O'Shea D, 2017 Dec 21, NK cells in childhood obesity are activated, metabolically stressed, and functionally deficient. JCI Insight, DOI: 10.1172/jci.insight.94939
Kinlen D, Cody D, O'Shea D, 2018 Jul 1, Complications of obesity. QJM, DOI: 10.1093/qjmed/hcx152
Glackin S, Mayne P, Kenny D, McMahon CJ, Cody D, 2017 Mar 10, Dilated cardiomyopathy secondary to vitamin D deficiency and hypocalcaemia in the Irish paediatric population: A case report. Ir Med J, DOI: 10.1093/qjmed/hcx152
Gonzalez Ballesteros LF, Ma NS, Gordon RJ, Ward L, Backeljauw P, Wasserman H, Weber DR, DiMeglio LA, Gagne J, Stein R, Cody D, Simmons K, Zimakas P, Topor LS, Agrawal S, Calabria A, Tebben P, Faircloth R, Imel EA, Casey L, Carpenter TO, 2017 Apr, Unexpected widespread hypophosphatemia and bone disease associated with elemental formula use in infants and children. Bone, DOI: 10.1016/j.bone.2017.02.003
Hawkes CP, Mavinkurve M, Fallon M, Grimberg A, Cody DC, 2015 Nov, Serial GH Measurement After Intravenous Catheter Placement Alone Can Detect Levels Above Stimulation Test Thresholds in Children. J Clin Endocrinol Metab, DOI: 10.1210/jc.2015-3102
Carolan E, Tobin LM, Mangan BA, Corrigan M, Gaoatswe G, Byrne G, Geoghegan J, Cody D, O'Connell J, Winter DC, Doherty DG, Lynch L, O'Shea D, Hogan AE, 2015 Jun 15, Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesity. J Immunol, DOI: 10.4049/jimmunol.1402945
McDarby V, Hevey D, Cody D, 2015 Apr, An overview of the role of social network sites in the treatment of adolescent diabetes. Diabetes Technol Ther, DOI: 10.1089/dia.2014.0308
Hawkes CP, McDarby V, Cody D, 2014 Aug, Fear of hypoglycemia in parents of children with type 1 diabetes. J Paediatr Child Health, DOI: 10.1111/jpc.12621
Bath L, Cody D, Krogvold L, Sundberg F, Bangstad HJ, 2014 May, Annual conference 2013 highlights. Pediatr Diabetes, DOI: 10.1111/pedi.12145
Carolan E, Hogan AE, Corrigan M, Gaotswe G, O'Connell J, Foley N, O'Neill LA, Cody D, O'Shea D, 2014 Mar, The impact of childhood obesity on inflammation, innate immune cell frequency, and metabolic microRNA expression. J Clin Endocrinol Metab, DOI: 10.1210/jc.2013-3529
O'Grady MJ, Hensey C, Fallon M, Hoey H, Murphy N, Costigan C, Cody D, 2013 Aug, Requirement for age-specific peak cortisol responses to insulin-induced hypoglycaemia in children. Eur J Endocrinol, DOI: 10.1530/EJE-13-0084
White M, Conroy J, Bullman H, Lever M, Daly E, Betts DR, Cody D, Crolla JA, Lynch SA, 2013, Duplication of 17q11.2 and Features of Albright Hereditary Osteodystrophy Secondary to Methylation Defects within the GNAS Cluster: Coincidence or Causal? Case Rep Genet, DOI: 10.1155/2013/764152
O'Grady MJ, Hensey C, Fallon M, Hoey H, Murphy N, Costigan C, Cody D, 2013 Jan, Lack of sensitivity of the 1-μg low-dose ACTH stimulation test in a paediatric population with suboptimal cortisol responses to insulin-induced hypoglycaemia. Clin Endocrinol (Oxf), DOI: 10.1111/j.1365-2265.2012.04474.x
O'Grady MJ, Cody D, 2011 Apr, Symptomatic Chiari 1 malformation after initiation of growth hormone therapy. J Pediatr, DOI: 10.1016/j.jpeds.2010.09.079
O'Grady MJ, Cody D, 2011 Mar, Subclinical hypothyroidism in childhood. Arch Dis Child, DOI: 10.1136/adc.2009.181800
Savage T, Clarke A, Costigan C, Loftus BG, Cody D, 2008 Jan, Services for children with diabetes. Ir Med J, DOI: 10.1136/adc.2009.181800
Cody D, 2007 Aug, Infant and toddler diabetes. Arch Dis Child, DOI: 10.1136/adc.2006.112896
Shenoy SD, Swift PG, Cody D, 2006 Mar, Growth impairment and adrenal suppression on low-dose inhaled beclomethasone. J Paediatr Child Health, DOI: 10.1111/j.1440-1754.2006.00814.x
Ng SM, Kumar Y, Cody D, Smith C, Didi M, 2005 Sep, The gonadotrophins response to GnRH test is not a predictor of neurological lesion in girls with central precocious puberty. J Pediatr Endocrinol Metab, DOI: 10.1111/j.1440-1754.2006.00814.x
Cody D, Kumar Y, Ng SM, Didi M, Smith C, 2003 Mar, The differing outcomes of hyperthyrotropinaemia. J Pediatr Endocrinol Metab, DOI: 10.1111/j.1440-1754.2006.00814.x

Funding Agency:National Children's Research Centre
Project Title:Investigating the impact of childhood obesity on innate immune cell function and metabolism, and their modulation by Metformin and Glucagon like peptide-1
Start Date/End Date:March 2017/February 2020
Name:Dr Andrew Hogan
DepartmentInstitute of Immunology
Institution:Maynooth University
Country:Ireland
Name:Professor Donal O’Shea
DepartmentEndocrinology & Obesity Immunology
Institution:St Vincent’s HealthCare Group
Country:Ireland