| Juric V, Düssmann H, Lamfers MLM, Prehn JHM, Rehm M, Murphy BM, 2021 May 12, Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM. Cells, DOI: 10.3390/cells10051182 |
| White K, Connor K, Clerkin J, Murphy BM, Salvucci M, O'Farrell AC, Rehm M, O'Brien D, Prehn JHM, Niclou SP, Lamfers MLM, Verreault M, Idbaih A, Verhaak R, Golebiewska A, Byrne AT, 2020 Dec, New hints towards a precision medicine strategy for IDH wild-type glioblastoma. Ann Oncol, DOI: 10.1016/j.annonc.2020.08.2336 |
| Noonan JJ, Jarzabek M, Lincoln FA, Cavanagh BL, Pariag AR, Juric V, Young LS, Ligon KL, Jahns H, Zheleva D, Prehn JHM, Rehm M, Byrne AT, Murphy BM, 2019 Dec 12, Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma. Cancers (Basel), DOI: 10.3390/cancers11122005 |
| Ryan AL, Fitzgerald MC, Ozsváth A, Twamley B, Buglyó P, Murphy BM, Griffith DM, 2019 Dec 2, Ni(II), Pd(II), and Pt(II) Complexes of the Hedgehog Pathway Inhibitor GANT61-D. Inorg Chem, DOI: 10.1021/acs.inorgchem.9b02632 |
| Salvucci M, Zakaria Z, Carberry S, Tivnan A, Seifert V, Kögel D, Murphy BM, Prehn JHM, 2019 Nov 12, System-based approaches as prognostic tools for glioblastoma. BMC Cancer, DOI: 10.1186/s12885-019-6280-2 |
| Lincoln FA, Imig D, Boccellato C, Juric V, Noonan J, Kontermann RE, Allgöwer F, Murphy BM, Rehm M, 2018 Nov 1, Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism. Cell Death Dis, DOI: 10.1038/s41419-018-1160-2 |
| Lindner AU, Lucantoni F, Varešlija D, Resler A, Murphy BM, Gallagher WM, Hill ADK, Young LS, Prehn JHM, 2018 Oct, Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers. J Mol Med (Berl), DOI: 10.1007/s00109-018-1675-0 |
| McKeon AM, Noonan J, Devocelle M, Murphy BM, Griffith DM, 2017 Oct 12, Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells. Chem Commun (Camb), DOI: 10.1039/c7cc04764a |
| Noonan J, Zarrer J, Murphy BM, 2016, Targeting Autophagy in Glioblastoma. Crit Rev Oncog, DOI: 10.1615/CritRevOncog.2016017008 |
| Weyhenmeyer BC, Noonan J, Würstle ML, Lincoln FA, Johnston G, Rehm M, Murphy BM, 2016 Sep 20, Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. Oncotarget, DOI: 10.18632/oncotarget.10973 |
| Murphy ÁC, Weyhenmeyer B, Noonan J, Kilbride SM, Schimansky S, Loh KP, Kögel D, Letai AG, Prehn JH, Murphy BM, 2014 Apr, Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis. Apoptosis, DOI: 10.1007/s10495-013-0935-2 |
| Murphy ÁC, Weyhenmeyer B, Schmid J, Kilbride SM, Rehm M, Huber HJ, Senft C, Weissenberger J, Seifert V, Dunst M, Mittelbronn M, Kögel D, Prehn JH, Murphy BM, 2013 May 16, Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach. Cell Death Dis, DOI: 10.1038/cddis.2013.157 |
| Weyhenmeyer B, Murphy AC, Prehn JH, Murphy BM, 2012 Oct, Targeting the anti-apoptotic Bcl-2 family members for the treatment of cancer. Exp Oncol, DOI: 10.1038/cddis.2013.157 |
| Thompson S, Pearson AN, Ashley MD, Jessick V, Murphy BM, Gafken P, Henshall DC, Morris KT, Simon RP, Meller R, 2011 Jun 3, Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. J Biol Chem, DOI: 10.1074/jbc.M110.197707 |
| Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC, 2010 Mar, Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J, DOI: 10.1096/fj.09-145870 |
| Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, Henshall DC, 2010 Mar, Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus. Cell Death Differ, DOI: 10.1038/cdd.2009.134 |
| Murphy N, Bonner HP, Ward MW, Murphy BM, Prehn JH, Henshall DC, 2008 Jul, Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures. J Neurochem, DOI: 10.1111/j.1471-4159.2008.05447.x |
| Engel T, Murphy BM, Schindler CK, Henshall DC, 2007 Dec, Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy Res, DOI: 10.1016/j.eplepsyres.2007.09.001 |
| Henshall DC, Murphy BM, 2008 Feb, Modulators of neuronal cell death in epilepsy. Curr Opin Pharmacol, DOI: 10.1016/j.coph.2007.07.005 |
| Murphy B, Dunleavy M, Shinoda S, Schindler C, Meller R, Bellver-Estelles C, Hatazaki S, Dicker P, Yamamoto A, Koegel I, Chu X, Wang W, Xiong Z, Prehn J, Simon R, Henshall D, 2007 Oct, Bcl-w protects hippocampus during experimental status epilepticus. Am J Pathol, DOI: 10.2353/ajpath.2007.070269 |
| Concannon CG, Koehler BF, Reimertz C, Murphy BM, Bonner C, Thurow N, Ward MW, Villunger A, Strasser A, Kögel D, Prehn JH, 2007 Mar 15, Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. Oncogene, DOI: 10.1038/sj.onc.1209974 |
| Yamamoto A, Schindler CK, Murphy BM, Bellver-Estelles C, So NK, Taki W, Meller R, Simon RP, Henshall DC, 2006 Dec, Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy. Exp Neurol, DOI: 10.1016/j.expneurol.2006.07.003 |
| Adrain C, Murphy BM, Martin SJ, 2005 Feb 11, Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B. J Biol Chem, DOI: 10.1074/jbc.M410915200 |
| Yang JY, Michod D, Walicki J, Murphy BM, Kasibhatla S, Martin SJ, Widmann C, 2004 Dec, Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions. Mol Cell Biol, DOI: 10.1128/MCB.24.23.10425-10436.2004 |
| Murphy BM, Creagh EM, Martin SJ, 2004 Aug 27, Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation. J Biol Chem, DOI: 10.1074/jbc.M402039200 |
| Creagh EM, Murphy BM, Duriez PJ, Duckett CS, Martin SJ, 2004 Jun 25, Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins. J Biol Chem, DOI: 10.1074/jbc.M313859200 |
| Murphy BM, O'Neill AJ, Adrain C, Watson RW, Martin SJ, 2003 Mar 3, The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C. J Exp Med, DOI: 10.1084/jem.20021862 |
