| De Barra C, O'Shea D, Hogan AE, 2023 Aug 19, NK cells vs. obesity: A tale of dysfunction & redemption. Clin Immunol, DOI: 10.1016/j.clim.2023.109744 |
| Cassidy FC, Kedia-Mehta N, Bergin R, Woodcock A, Berisha A, Bradley B, Booth E, Jenkins BJ, Ryan OK, Jones N, Sinclair LV, O'Shea D, Hogan AE, 2023 Jun 20, Glycogen-fuelled metabolism supports rapid mucosal-associated invariant T cell responses. Proc Natl Acad Sci U S A, DOI: 10.1073/pnas.2300566120 |
| De Barra C, Khalil M, Mat A, O'Donnell C, Shaamile F, Brennan K, O'Shea D, Hogan AE, 2023 Jul, Glucagon-like peptide-1 therapy in people with obesity restores natural killer cell metabolism and effector function. Obesity (Silver Spring), DOI: 10.1002/oby.23772 |
| Kedia-Mehta N, Pisarska MM, Rollings C, O'Neill C, De Barra C, Foley C, Wood NAW, Wrigley-Kelly N, Veerapen N, Besra G, Bergin R, Jones N, O'Shea D, Sinclair LV, Hogan AE, 2023 Apr 18, The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis. Sci Signal, DOI: 10.1126/scisignal.abo2709 |
| Kedia-Mehta N, Hogan AE, 2022, MAITabolism(2) - the emerging understanding of MAIT cell metabolism and their role in metabolic disease. Front Immunol, DOI: 10.3389/fimmu.2022.1108071 |
| Gallagher C, Mahon JM, O'Neill C, Cassidy FC, Dunbar H, De Barra C, Cadden C, Pisarska MM, Wood NAW, Masterson JC, McNamee EN, Schrumpf E, English K, O'Shea D, Tobin AM, Hogan AE, 2023 Jun, Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu. J Invest Dermatol, DOI: 10.1016/j.jid.2022.11.011 |
| Kelly NEW, De Barra C, Shaamile F, Holland A, Shaw L, Mallon PWG, O'Connell J, Hogan AE, O'Shea D, 2023 Jan, Antigen specific T cells in people with obesity at five months following ChAdOx1 COVID-19 vaccination. Int J Obes (Lond), DOI: 10.1038/s41366-022-01235-8 |
| Savinelli S, Wrigley Kelly NE, Feeney ER, O'Shea DB, Hogan AE, Overton ET, Landay AL, Mallon PW, 2022 Sep 1, Obesity in HIV infection: host-pathogen interaction. AIDS, DOI: 10.1097/QAD.0000000000003281 |
| Boland L, Bitterlich LM, Hogan AE, Ankrum JA, English K, 2022, Translating MSC Therapy in the Age of Obesity. Front Immunol, DOI: 10.3389/fimmu.2022.943333 |
| Schmidt V, Hogan AE, Fallon PG, Schwartz C, 2022, Obesity-Mediated Immune Modulation: One Step Forward, (Th)2 Steps Back. Front Immunol, DOI: 10.3389/fimmu.2022.932893 |
| Wrigley Kelly NE, Kenny G, Cassidy FC, Garcia-Leon AA, De Barra C, Mallon PWG, Hogan AE, O'Shea D, 2022 Oct, Individuals with obesity who survive SARS-CoV-2 infection have preserved antigen-specific T cell frequencies. Obesity (Silver Spring), DOI: 10.1002/oby.23526 |
| Bergin R, Kinlen D, Kedia-Mehta N, Hayes E, Cassidy FC, Cody D, O'Shea D, Hogan AE, 2022 Jun, Mucosal-associated invariant T cells are associated with insulin resistance in childhood obesity, and disrupt insulin signalling via IL-17. Diabetologia, DOI: 10.1007/s00125-022-05682-w |
| Schwartz C, Schmidt V, Deinzer A, Hawerkamp HC, Hams E, Bayerlein J, Röger O, Bailer M, Krautz C, El Gendy A, Elshafei M, Heneghan HM, Hogan AE, O'Shea D, Fallon PG, 2022 Mar 9, Innate PD-L1 limits T cell-mediated adipose tissue inflammation and ameliorates diet-induced obesity. Sci Transl Med, DOI: 10.1126/scitranslmed.abj6879 |
| Cooper AJR, Clegg J, Cassidy FC, Hogan AE, McLoughlin RM, 2022 Jan 12, Human MAIT Cells Respond to Staphylococcus aureus with Enhanced Anti-Bacterial Activity. Microorganisms, DOI: 10.3390/microorganisms10010148 |
| Kedia-Mehta N, Tobin L, Zaiatz-Bittencourt V, Pisarska MM, De Barra C, Choi C, Elamin E, O'Shea D, Gardiner CM, Finlay DK, Hogan AE, 2021 Nov 9, Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity. Blood Adv, DOI: 10.1182/bloodadvances.2021005047 |
| Moynagh PN, Hogan AE, 2021 Oct, The IRX(3)some factor in macrophages. Nat Immunol, DOI: 10.1038/s41590-021-01032-x |
| McCarthy C, O'Donnell CP, Kelly NEW, O'Shea D, Hogan AE, 2021 May, COVID-19 severity and obesity: are MAIT cells a factor? Lancet Respir Med, DOI: 10.1016/S2213-2600(21)00140-5 |
| O'Neill C, Cassidy FC, O'Shea D, Hogan AE, 2021 Mar 30, Mucosal Associated Invariant T Cells in Cancer-Friend or Foe? Cancers (Basel), DOI: 10.3390/cancers13071582 |
| Hams E, Roberts J, Bermingham R, Hogan AE, O'Shea D, O'Neill L, Fallon PG, 2020, Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity. Front Immunol, DOI: 10.3389/fimmu.2020.01966 |
| Pisarska MM, Dunne MR, O'Shea D, Hogan AE, 2020 Aug, Interleukin-17 producing mucosal associated invariant T cells - emerging players in chronic inflammatory diseases? Eur J Immunol, DOI: 10.1002/eji.202048645 |
| Brien AO, Kedia-Mehta N, Tobin L, Veerapen N, Besra GS, Shea DO, Hogan AE, 2020 Nov, Targeting mitochondrial dysfunction in MAIT cells limits IL-17 production in obesity. Cell Mol Immunol, DOI: 10.1038/s41423-020-0375-1 |
| Giannoudaki E, Hernandez-Santana YE, Mulfaul K, Doyle SL, Hams E, Fallon PG, Mat A, O'Shea D, Kopf M, Hogan AE, Walsh PT, 2019 Sep 5, Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction. Nat Commun, DOI: 10.1038/s41467-019-11944-w |
| Melo AM, O'Brien AM, Phelan JJ, Kennedy SA, Wood NAW, Veerapen N, Besra GS, Clarke NE, Foley EK, Ravi A, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, Conroy MJ, Hogan AE, O'Sullivan J, Dunne MR, 2019, Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma. Front Immunol, DOI: 10.3389/fimmu.2019.01580 |
| O'Brien A, Loftus RM, Pisarska MM, Tobin LM, Bergin R, Wood NAW, Foley C, Mat A, Tinley FC, Bannan C, Sommerville G, Veerapen N, Besra GS, Sinclair LV, Moynagh PN, Lynch L, Finlay DK, O'Shea D, Hogan AE, 2019 Jun 15, Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses. J Immunol, DOI: 10.4049/jimmunol.1801600 |
| O'Shea D, Hogan AE, 2019 Apr 23, Dysregulation of Natural Killer Cells in Obesity. Cancers (Basel), DOI: 10.3390/cancers11040573 |
| Brennan K, O'Leary BD, Mc Laughlin D, Kinlen D, Molloy EJ, Cody D, Paran S, McAuliffe FM, Hogan AE, Doyle SL, 2019 Jul, Nucleic acid cytokine responses in obese children and infants of obese mothers. Cytokine, DOI: 10.1016/j.cyto.2019.03.015 |
| Brennan K, O'Leary BD, Mc Laughlin D, Breen EP, Connolly E, Ali N, O'Driscoll DN, Ozaki E, Mahony R, Mulfaul K, Ryan AM, Ni Chianain A, McHugh A, Molloy EJ, Hogan AE, Paran S, McAuliffe FM, Doyle SL, 2018 Aug 15, Type 1 IFN Induction by Cytosolic Nucleic Acid Is Intact in Neonatal Mononuclear Cells, Contrasting Starkly with Neonatal Hyporesponsiveness to TLR Ligation Due to Independence from Endosome-Mediated IRF3 Activation. J Immunol, DOI: 10.4049/jimmunol.1700956 |
| Tobin LM, Mavinkurve M, Carolan E, Kinlen D, O'Brien EC, Little MA, Finlay DK, Cody D, Hogan AE, O'Shea D, 2017 Dec 21, NK cells in childhood obesity are activated, metabolically stressed, and functionally deficient. JCI Insight, DOI: 10.1172/jci.insight.94939 |
| Khan F, Mat A, Hogan AE, Kent BD, Eigenheer S, Corrigan MA, O'Shea D, Butler MW, 2017 Dec 1, Preliminary asthma-related outcomes following glucagon-like peptide 1 agonist therapy. QJM, DOI: 10.1093/qjmed/hcx125 |
| Boulenouar S, Michelet X, Duquette D, Alvarez D, Hogan AE, Dold C, O'Connor D, Stutte S, Tavakkoli A, Winters D, Exley MA, O'Shea D, Brenner MB, von Andrian U, Lynch L, 2017 Feb 21, Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity. Immunity, DOI: 10.1016/j.immuni.2017.01.008 |
| Lynch L, Hogan AE, Duquette D, Lester C, Banks A, LeClair K, Cohen DE, Ghosh A, Lu B, Corrigan M, Stevanovic D, Maratos-Flier E, Drucker DJ, O'Shea D, Brenner M, 2016 Sep 13, iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy. Cell Metab, DOI: 10.1016/j.cmet.2016.08.003 |
| Hams E, Bermingham R, Wurlod FA, Hogan AE, O'Shea D, Preston RJ, Rodewald HR, McKenzie AN, Fallon PG, 2016 Feb, The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism. FASEB J, DOI: 10.1096/fj.15-277822 |
| Gaoatswe G, Kent BD, Corrigan MA, Nolan G, Hogan AE, McNicholas WT, O'Shea D, 2015 Oct 1, Invariant Natural Killer T Cell Deficiency and Functional Impairment in Sleep Apnea: Links to Cancer Comorbidity. Sleep, DOI: 10.5665/sleep.5062 |
| Carolan E, Tobin LM, Mangan BA, Corrigan M, Gaoatswe G, Byrne G, Geoghegan J, Cody D, O'Connell J, Winter DC, Doherty DG, Lynch L, O'Shea D, Hogan AE, 2015 Jun 15, Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesity. J Immunol, DOI: 10.4049/jimmunol.1402945 |
| Woods CP, Corrigan M, Gathercole L, Taylor A, Hughes B, Gaoatswe G, Manolopoulos K, Hogan AE, O'Connell J, Stewart PM, Tomlinson JW, O'Shea D, Sherlock M, 2015 Apr, Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT). J Clin Endocrinol Metab, DOI: 10.1210/jc.2014-4120 |
| Ip BC, Hogan AE, Nikolajczyk BS, 2015 Feb, Lymphocyte roles in metabolic dysfunction: of men and mice. Trends Endocrinol Metab, DOI: 10.1016/j.tem.2014.12.001 |
| Yang S, Wang B, Humphries F, Hogan AE, O'Shea D, Moynagh PN, 2014 Dec 18, The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance. Immunity, DOI: 10.1016/j.immuni.2014.11.013 |
| Carolan E, Hogan AE, Corrigan M, Gaotswe G, O'Connell J, Foley N, O'Neill LA, Cody D, O'Shea D, 2014 Mar, The impact of childhood obesity on inflammation, innate immune cell frequency, and metabolic microRNA expression. J Clin Endocrinol Metab, DOI: 10.1210/jc.2013-3529 |
| Hogan AE, Gaoatswe G, Lynch L, Corrigan MA, Woods C, O'Connell J, O'Shea D, 2014 Apr, Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus. Diabetologia, DOI: 10.1007/s00125-013-3145-0 |
| Zeng SG, Ghnewa YG, O'Reilly VP, Lyons VG, Atzberger A, Hogan AE, Exley MA, Doherty DG, 2013 Aug 15, Human invariant NKT cell subsets differentially promote differentiation, antibody production, and T cell stimulation by B cells in vitro. J Immunol, DOI: 10.4049/jimmunol.1202223 |
| Mangan BA, Dunne MR, O'Reilly VP, Dunne PJ, Exley MA, O'Shea D, Scotet E, Hogan AE, Doherty DG, 2013 Jul 1, Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells. J Immunol, DOI: 10.4049/jimmunol.1300121 |
| O'Shea D, Corrigan M, Dunne MR, Jackson R, Woods C, Gaoatswe G, Moynagh PN, O'Connell J, Hogan AE, 2013 Nov, Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection. Int J Obes (Lond), DOI: 10.1038/ijo.2013.16 |
| Lynch L, Nowak M, Varghese B, Clark J, Hogan AE, Toxavidis V, Balk SP, O'Shea D, O'Farrelly C, Exley MA, 2012 Sep 21, Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity, DOI: 10.1016/j.immuni.2012.06.016 |
| Farah N, Hogan AE, O'Connor N, Kennelly MM, O'Shea D, Turner MJ, 2012 Oct, Correlation between maternal inflammatory markers and fetomaternal adiposity. Cytokine, DOI: 10.1016/j.cyto.2012.05.024 |
| O'Reilly V, Zeng SG, Bricard G, Atzberger A, Hogan AE, Jackson J, Feighery C, Porcelli SA, Doherty DG, 2011, Distinct and overlapping effector functions of expanded human CD4+, CD8α+ and CD4-CD8α- invariant natural killer T cells. PLoS One, DOI: 10.1371/journal.pone.0028648 |
| Michielsen AJ, Hogan AE, Marry J, Tosetto M, Cox F, Hyland JM, Sheahan KD, O'Donoghue DP, Mulcahy HE, Ryan EJ, O'Sullivan JN, 2011, Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer. PLoS One, DOI: 10.1371/journal.pone.0027944 |
| Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, O'Reilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, O'Connell J, O'Shea D, 2011 Nov, Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis. Diabetologia, DOI: 10.1007/s00125-011-2232-3 |
| Hogan AE, Corrigan MA, O'Reilly V, Gaoatswe G, O'Connell J, Doherty DG, Lynch L, O'Shea D, 2011 Sep, Cigarette smoke alters the invariant natural killer T cell function and may inhibit anti-tumor responses. Clin Immunol, DOI: 10.1016/j.clim.2011.01.011 |
| Hogan AE, O'Reilly V, Dunne MR, Dere RT, Zeng SG, O'Brien C, Amu S, Fallon PG, Exley MA, O'Farrelly C, Zhu X, Doherty DG, 2011 Aug, Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide. Clin Immunol, DOI: 10.1016/j.clim.2011.03.016 |
| Kenna T, O'Brien M, Hogan AE, Exley MA, Porcelli SA, Hegarty JE, O'Farrelly C, Doherty DG, 2007 Apr, CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver. Cancer Immunol Immunother, DOI: 10.1007/s00262-006-0215-x |
Andrew Hogan