Ethical, Legal & Regulatory Requirements


All investigators supported by the NCRC must ensure that the necessary ethical, legal, and regulatory requirements are met before undertaking their research. Further to this, evidence that all the required licences and approvals have been obtained by the Principal Investigator, and their research team where appropriate, must be submitted to the NCRC prior to the commencement of the research.

Research Ethics

Regardless of where it takes place, research funded through the NCRC adheres to the highest ethical standards. Ethical approval is required for all research supported by the NCRC that involves human participants, human material (including tissue), or animals, and written evidence of this approval must be submitted to the NCRC prior to the commencement of the research.

Health Products Regulatory Authority

The Health Products Regulatory Authority (HPRA) is responsible for regulating, amongst other things, clinical trials, and the use of animals for research. If research supported by the NCRC includes a study that requires HPRA approval, then a copy of the approval must be provided to the NCRC prior to the commencement of the study.

Good Research Practice

All investigators supported by the NCRC are required to follow Good Research Practice as outlined in the:

National Policy Statement on Ensuring Research Integrity in Ireland.pdf

Data Protection

All data generated in the course of NCRC supported research must be treated in accordance with the Data Protection Acts 1988 and 2003. Please see the Guidelines on Research in the Health Sector for advice on how health research can be carried out within with the framework of Irish data protection legislation.