Emergency Medicine

Creation of new knowledge through research is one pillar of the Department of Emergency Medicine. An Emergency Medicine investigative programme is translational in character. By virtue of overlapping interests from faculty with expertise in both basic and clinical investigation, ideas, technology and treatments can be tested at the bench and in patients. Observations in patients can be examined in mechanistic detail. Finally, evidence-based findings can be translated into guidelines, policy and protocols at a local and national level. In Children’s Health Ireland at Crumlin, emergency care covers acute clinical care provision from the primary care to the quaternary care patient.

We openly collaborate and lead on local projects or on projects in PERUKI – the Paediatric Emergency Research (PEM) collaborative for the United Kingdom and Ireland. PERUKI has 60+ affiliated sites and is a member of PERN (Pediatric Emergency Research Networks) the global PEM research network.

Topics of current and future research include trauma, sedation and analgesia,  pneumonia, urinary tract infections, ultrasound, sickle cell disease, haemophilia, adolescent health, critical care, complex care, education, knowledge translation, overcrowding,  ‘big data’ analysis,  and performance indicators.

We take an active role in encouraging and mentoring the acquisition of research skills to continue improving the emergency care of children through high quality research.

Current Trials & Studies

Study NameStudy TitleStudy TypeSponsorSponsor Type
MAGPIEPhase 3, multicenter, randomized, double-blinded, placebo-controlled trial of methoxyflurane (PENTHROX) for the treatment of acute pain in children and adolescents from 6 to less than 18 years of age (presenting to ED with minor trauma)Clinical TrialMedical Developments International LimitedIndustry Sponsored
CUPIDChildren’s unscheduled primary and emergency care in Ireland: decision making, trends, outcomes and parental perspectivesObservationalUniversity College DublinAcademic-Investigator Led
CERACOVID-19 Emergency Response Assessment A Professional SurveySocial ResearchItern, PERUKIInvestigator Led
CUPID COVID-19Emergency Department Attendance by Paediatric Patients during COVID-19 ProjectObservational StudyUniversity College DublinAcademic-Investigator Led

Past Trials & Studies

Study NameStudy TitleStudy TypeSponsorSponsor Type
SCC01/SNIFA Randomised Controlled Double-Blind Trial of Intranasal Fentanyl versus Intravenous Morphine in the Emergency Department Treatment of Severe Painful Sickle Cell Crises in ChildrenClinical TrialUniversity College DublinAcademic-Investigator Led
RESP_301_2010A Randomised Trial of Single Dose Oral Dexamethasone versus Multi-Dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children Who Attend the Emergency DepartmentClinical TrialUniversity College DublinAcademic-Investigator Led
Febrile IllnessTranscriptional biosignatures in undifferentiated febrile illness in childrenNon-Interventional Clinical Trial
SedationDevelopment of a Sedation Registry for a Paediatric Procedural Sedation Programme in a Tertiary Paediatric Emergency DepartmentNon-Interventional Study
KPIFeasibility analysis of Key Performance Indicators Emergency Department in IrelandNon-Interventional Study
CAP-ITEfficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia (CAP): A randomised controlled trialClinical TrialNIHR/UCLAcademic-Investigator Led
VR–IVCVirtual Reality Hypnotherapy for IV Cannulation StudyInterventional