Creation of new knowledge through research is one pillar of the Department of Emergency Medicine. An Emergency Medicine investigative programme is translational in character. By virtue of overlapping interests from faculty with expertise in both basic and clinical investigation, ideas, technology and treatments can be tested at the bench and in patients. Observations in patients can be examined in mechanistic detail at the bench. Finally, specific findings can be translated into policy and protocols at a local and national level. In OLCHC, emergency care covers acute clinical care provision from the primary care to the quaternary care patient.
We collaborate and lead on local projects and on projects with PERUKI – the Paediatric Emergency Research (PEM) collaborative for the United Kingdom and Ireland with 51 centres, which is itself a formal core member of PERN (Pediatric Emergency Research Networks) the global PEM research network.
The Paediatric Emergency Research Unit has secured grant funding in excess of €3M and has facilitated PhD and MD students in both PEM and Emergency Medicine research. The topics of these research projects include trauma, asthma, prehospital pain, acute pain, sickle cell disease, sedation, education, knowledge translation, performance indicators and novel point of care blood testing.
This research has resulted multiple awards at both a national and international level by the Irish Association of Emergency Medicine, Pediatric Academic Societies (USA), Academic Pediatric Association (USA) and National Center of Advancing Translational Sciences, National Institute of Health (USA). Current local project research areas include; critical care provision, complex care provision, safety and prevention in trauma, sedation, checklists, cognitive aides, point of care ultrasound and point of care testing at triage.
We take an active role in encouraging and mentoring the acquisition of research skills by PEM researchers to continue improving the emergency care of children through high quality research.
| Study Name | Study Title | Study Type | Sponsor | Sponsor Type |
|---|---|---|---|---|
| MAGPIE | Phase 3, multicenter, randomized, double-blinded, placebo-controlled trial of methoxyflurane (PENTHROX) for the treatment of acute pain in children and adolescents from 6 to less than 18 years of age (presenting to ED with minor trauma) | Clinical Trial | Medical Developments International Limited | Industry Sponsored |
| Study Name | Study Title | Study Type | Sponsor | Sponsor Type |
|---|---|---|---|---|
| SCC01/SNIF | A Randomised Controlled Double-Blind Trial of Intranasal Fentanyl versus Intravenous Morphine in the Emergency Department Treatment of Severe Painful Sickle Cell Crises in Children | Clinical Trial | University College Dublin, NCRC | Academic – Investigator Led |
| RESP_301_2010 | A Randomised Trial of Single Dose Oral Dexamethasone versus Multi-Dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children Who Attend the Emergency Department | Clinical Trial | University College Dublin, NCRC | Academic – Investigator Led |
| Febrile Illness | Transcriptional biosignatures in undifferentiated febrile illness in children | Non-Interventional Clinical Trial | NCRC | Academic – Investigator Led |
| Sedation | Development of a Sedation Registry for a Paediatric Procedural Sedation Programme in a Tertiary Paediatric Emergency Department | Non-Interventional Study | NCRC | Academic – Investigator Led |
| KPI | Feasibility analysis of Key Performance Indicators Emergency Department in Ireland | Non-Interventional Study | Health Research Board | Academic – Investigator Led |
