Creation of new knowledge through research is one pillar of the Department of Emergency Medicine. An Emergency Medicine investigative programme is translational in character. By virtue of overlapping interests from faculty with expertise in both basic and clinical investigation, ideas, technology and treatments can be tested at the bench and in patients. Observations in patients can be examined in mechanistic detail. Finally, evidence-based findings can be translated into guidelines, policy and protocols at a local and national level. In Children’s Health Ireland at Crumlin, emergency care covers acute clinical care provision from the primary care to the quaternary care patient.
We openly collaborate and lead on local projects or on projects in PERUKI – the Paediatric Emergency Research (PEM) collaborative for the United Kingdom and Ireland. PERUKI has 60+ affiliated sites and is a member of PERN (Pediatric Emergency Research Networks) the global PEM research network.
Topics of current and future research include trauma, sedation and analgesia, pneumonia, urinary tract infections, ultrasound, sickle cell disease, haemophilia, adolescent health, critical care, complex care, education, knowledge translation, overcrowding, ‘big data’ analysis, and performance indicators.
We take an active role in encouraging and mentoring the acquisition of research skills to continue improving the emergency care of children through high quality research.
| Study Name | Study Title | Study Type | Sponsor | Sponsor Type |
|---|---|---|---|---|
| MAGPIE | Phase 3, multicenter, randomized, double-blinded, placebo-controlled trial of methoxyflurane (PENTHROX) for the treatment of acute pain in children and adolescents from 6 to less than 18 years of age (presenting to ED with minor trauma) | Clinical Trial | Medical Developments International Limited | Industry Sponsored |
| CUPID | Children’s unscheduled primary and emergency care in Ireland: decision making, trends, outcomes and parental perspectives | Observational | University College Dublin | Academic-Investigator Led |
| CERA | COVID-19 Emergency Response Assessment A Professional Survey | Social Research | Itern, PERUKI | Investigator Led |
| CUPID COVID-19 | Emergency Department Attendance by Paediatric Patients during COVID-19 Project | Observational Study | University College Dublin | Academic-Investigator Led |
| Study Name | Study Title | Study Type | Sponsor | Sponsor Type |
|---|---|---|---|---|
| SCC01/SNIF | A Randomised Controlled Double-Blind Trial of Intranasal Fentanyl versus Intravenous Morphine in the Emergency Department Treatment of Severe Painful Sickle Cell Crises in Children | Clinical Trial | University College Dublin | Academic-Investigator Led |
| RESP_301_2010 | A Randomised Trial of Single Dose Oral Dexamethasone versus Multi-Dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children Who Attend the Emergency Department | Clinical Trial | University College Dublin | Academic-Investigator Led |
| Febrile Illness | Transcriptional biosignatures in undifferentiated febrile illness in children | Non-Interventional Clinical Trial | ||
| Sedation | Development of a Sedation Registry for a Paediatric Procedural Sedation Programme in a Tertiary Paediatric Emergency Department | Non-Interventional Study | ||
| KPI | Feasibility analysis of Key Performance Indicators Emergency Department in Ireland | Non-Interventional Study | ||
| CAP-IT | Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia (CAP): A randomised controlled trial | Clinical Trial | NIHR/UCL | Academic-Investigator Led |
| VR–IVC | Virtual Reality Hypnotherapy for IV Cannulation Study | Interventional |
